颈动脉钙化与缺血性脑血管病  

Carotid artery calcification and ischemic cerebrovascular disease

作　　者：张海侠[1] 王刘敏 刘新峰[1] 

机构地区：[1]南京大学医学院附属金陵医院,210002

出　　处：《国际脑血管病杂志》2015年第3期204-208,共5页International Journal of Cerebrovascular Diseases

基　　金：国家青年科学基金（31300900,81200892）

摘　　要：颈动脉钙化是发生在颈动脉管壁上的钙沉积，当发生在颈动脉粥样硬化斑块内时临床意义较大，是进展性动脉粥样硬化的标志。近年来，对颈动脉钙化的发生机制和影像学检测方法的研究不断进展和更新。此外，关于颈动脉斑块钙化与缺血性脑血管病的相关性及其对治疗决策的影响也是研究的热点。然而，颈动脉钙化的利与弊一直存在争论，有学者认为颈动脉钙化是保护性因素，但也有学者认为其会促进斑块易损性。文章从上述几个方面对颈动脉钙化的研究进展进行了综述。Carotid artery calcification is a calcium deposition on arterial wals. It has a great clinical significance when it occurs within atherosclerotic plaques, which is a marker of the progressive atherosclerosis. In recent years, the studies on the mechanism of carotid artery calcification and imaging detection methods are continuously advancing and being updated. In addition, the correlation between carotid plaque calcification and ischemic cerebrovascular disease and the effect on its therapeutic decisions are also the research foci. However, there have been controversies about the advantages and disadvantages of carotid artery calcification. Some researchers believe that carotid artery calcifications are a protective factor, but others believe that they may promote the plaque vulnerability. This article reviews the recent progress in research on carotid artery calcification from the above aspects.

关 键 词：颈动脉疾病 斑块 动脉粥样硬化 钙质沉着症 卒中 脑缺血 体层摄影术 X线计算机 血管造影术 

分 类 号：R743[医药卫生—神经病学与精神病学]