改良小梁切除术联合神经保护疗法的临床观察  

Clinical Observation of Modified Phacotrabectomy Combined with Neuroprotection Treatment

作　　者：刘凤茹[1] 陈志良[1] 贾平凡[1] 

机构地区：[1]天津市第一中心医院,300192

出　　处：《天津医药》2002年第8期463-465,共3页Tianjin Medical Journal

摘　　要：目的:观察改良小梁切除术联合神经保护疗法的临床疗效。方法:40例（48只眼）绝对期青光眼行改良小梁切除术,同时加服神经保护及血管扩张药（改良组）,并与34例（40只眼）行传统小梁切除术（对照组）比较。结果:改良组术前平均眼压（35.6±8.8）mmHg,术后平均眼压（17.5±6.8）mmHg;对照组术前平均眼压（34.7±6.7）mmHg,术后平均眼压（20.3±8.1）mmHg,差异有非常显著性（P<0.01）。改良组术后12只眼,对照组6只眼恢复光感以上视力,差异无显著性（P>0.05）。两组术后各随访32只眼,平均（23.5± 6.7）个月。改良组平均眼压（21.5±6.5）mmHg,对照组平均眼压（25.7±6.5）mmHg,差异有显著性（P<0.05）。改良组7只眼,对照组2只眼维持光感以上视力,差异有非常显著性（P<0.01）。结论:改良手术成功的关键是保持手术瘘道的通畅,神经保护疗法对视神经纤维早期机能恢复是有益的,失明4个月内的青光眼行手术治疗,有望恢复有用的视力。Objective: To evaluate the clinical results of modified trabeculectomy combined with neuroprotection treatment. Methods: forty-eigth eyes of 40 patients who underwent modified trabeculectomy and received postoperative neuroprotection and vasodilator were compared with 40 eyes of 34 patients who underwent traditional trabeculectomy. Results: The mean preoperative intraocular pressure (IOP) was (35.6±8.8) mmHg in modified group and (34.7±6.7) mmHg in control group. The mean postoperative IOP was (17.5 ± 6. 8)mmHg in modified group and (20.3± 8. l)mmHg in control group.There was a significant difference between them(P<0.01) .The visual acuity was better than light perception in 12 eyes in modified group and 6 eyes in control group (P>0.05).Thirty-two eyes were followed up in each group with a mean of (23. 5 ± 6.7)months.The mean IOPwas (21. 5 ±6. 5) mmHg in modified group and (25.7±6.5) mmHg in control group (P<0.05) .Visual acuity was better than light perception in 7 eyes in modified group and 2 eyes in control group respectively (P<0.01) .Conclusion: The key point of a successful modified operation is to keep the fistula opened. Neuroprotection treatment is beneficial to early recovery of neurofiber function. The operation for glaucoma patients within four-month blindness can make it hopeful to recover the visual acuity.

关 键 词：改良小梁切除术 神经保护疗法 临床观察 神经保护药 血管舒张药 青光眼 

分 类 号：R775[医药卫生—眼科] R779.6[医药卫生—临床医学]