药物中毒性视神经病变的研究进展  

Research progress of drug-induced toxic optic neuropathy

作　　者：王影[1] 童绎[2] 

机构地区：[1]中国中医科学院眼科医院,北京100040 [2]福建医科大学附属第一医院,福州350005

出　　处：《实用药物与临床》2015年第4期459-462,共4页Practical Pharmacy and Clinical Remedies

摘　　要：中毒性视神经病变在临床十分常见,是复杂的多因素疾病,中毒的原因涉及营养、环境、毒性物质和基因等因素。中毒性视功能损伤与药物治疗、酒精等因素密切相关,在发达或发展中国家均有发生。典型的中毒性视神经病变是渐进性、双侧无痛性视力下降伴有中心或旁中心暗点。药物(包括中草药)所致的视神经病变更应引起重视,早期诊断和前期干预可能减轻甚至防止视力损害的发生。Toxic optic neuropathy is a complex,multifactorial disease. Etiology includes nutritional,environmental,toxicologic and genetic factors. Toxic amblyopia relating to drug treatment or alcohol abuse is encountered in the developed or developing country. Typically,toxic optic neuropathy is progressive,with bilateral symmetrical painless visual loss causing central or paracentral scotoma. Doctors should pay more attention on drugs（ including Chinese herbal medicine）-induced optic neuropathy,early detection and prompt intervention may ameliorate and even prevent severe visual deficit.

关 键 词：中毒性视神经病变 药物 

分 类 号：R774.6[医药卫生—眼科]