误诊为再障的全血细胞减少患者转化为急性白血病一例报道及文献复习  

A case report on misdiagnosed as aplastic anemia in a patient with pencytopenia transformed to acute leukemia in six months and literature review

作　　者：孙爱红[1] 王方方[1] 刘媛[1] 管俊[1] 裴孝平[1] 马莉[1] 吴蔚[1] 

机构地区：[1]江苏省苏北人民医院血液科,225001

出　　处：《中国优生与遗传杂志》2015年第4期104-105,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的回顾分析一例诊断为再障患者,半年后复查骨髓已为急性白血病(M2),分析误诊原因,杜绝这类患者的误诊。方法回顾分析该患者初诊时资料,如临床资料,血常规中红细胞参数,如红细胞平均体积、平均血红蛋白量,及多部位骨髓涂片特点。结果患者因贫血就诊,初诊时经过骨髓涂片、活检诊断为再障,给予促造血治疗效果不明显,半年后复诊诊为急性白血病。讨论和结论回顾维也纳诊断ICUS诊断标准,分析全细胞减少症患者,与诊断标准不典型指标不能忽视,重视这些指标可杜绝这类疾病的误诊。objective：In order to prohibit such patients misdiagnosed a case of 48 Yrs female patient diagnosed with aplastic anemia,who was diagnosed as acute leukemia（M2）six months after,was presented and retrospectively analyzed in this paper. Methods：A newly diagnosed with aplastic anemia was retrospectively analysed about her basic information such as clinical data,periperal blood red blood cell（RBC）parameters including mean corpuscular volume（MCV）,mean corpuscular hemoglobin（MCH）,and characteristics of multi-site bone marrow smear. Results：The patient was initially diagnosed by aspiration and biopsy of her bone marrow because of anemia and received therapy of promoting hematopoietic but there was no significant effect. She was diagnosed for acute leukemia in six months when she revisit our department. Discussion and Conclusion：Diagnostic criteria for ICUS in Vienna was reviewed here. Such patients with pencytopenia must be analysised thoroughly in her/his peripheral blood smear and multi-site bone marrow samples. Misdiagnosis of these diseased may be prevented.

关 键 词：再障 急性白血病 误诊 全血细胞减少症 

分 类 号：R733.71[医药卫生—肿瘤]