两种化疗方案治疗三阴乳腺癌患者疗效对比  

Therapeutic comparison of the two combined chemotherapies for treating the patients with triple-negative breast cancer

作　　者：张云[1] 于健[2] 张璐[1] 

机构地区：[1]武警后勤学院附属医院肝胆外科,天津300162 [2]武警后勤学院附属医院普外科,天津300162

出　　处：《武警后勤学院学报（医学版）》2015年第3期188-190,共3页Journal of Logistics University of PAP（Medical Sciences）

摘　　要：【目的】比较蒽环类或卡铂联合紫杉类治疗三阴乳腺癌患者的临床疗效。【方法】收集2004年1月至2008年6月收治我院的60例三阴型乳腺癌患者临床资料。其中使用蒽环类联合紫杉类(ET方案)化疗的30例患者作为组1,使用卡铂联合紫杉类(TC方案)化疗的30例患者作为组2。对比两组患者治疗后的疾病控制率、毒副反应发生率及生存时间。【结果】两组患者治疗后的疾病控制率、毒副反应发生率、生存时间比较,差异均无统计学意义(P>0.05)。【结论】TC方案与ET方案均能有效地治疗三阴型乳腺癌,其治疗效果相当,且并发症较少,但仍需循证医学证据支持,并制定标准的治疗方案。[ Objective] Therapeutic comparison of combining Anthracycline or Carboplatin with Taxol for treating the patients with triple-negative breast cancer. [ Methods ]The clinical data of 60 patients with triple-negative breast cancer treated in our hospital were analyzed retrospectively from January 2004 to June 2008. The patients in group 1 were treated with Anthracycline and Taxol, and the patients in group 2 were treated with Carboplatin and Taxol, in which the disease control rate, the occurrence rate of toxicity and survival time were evaluated. [ Results]The disease control rate, the occnrence rate of toxicity and survival time were close in comparison of two group, with no statistical significance （P〉0.05）. [Conclusion]Both TC and ET chemotherapy were effective for treating triple-negative breast cancer, and the difference was of no significance in clinical effect between two groups with fewer implications. Further evidence of evidence based medicine and the standard therapeutic regimen were needed.

关 键 词：三阴型乳腺癌 化疗 蒽环类 紫杉醇 卡铂 

分 类 号：R737.9[医药卫生—肿瘤]