补气化痰活血方对进展性缺血性卒中患者头部CT缺血灶的影响  

Effects of Buqi Huatan Huoxue recipe on head CT ischemic focus in patients with progressive ischemic stroke

作　　者：付中应[1] 李向荣[1] 易宣超[1] 付磊[1] 张鹏[1] 林旭明[1] 

机构地区：[1]湖南中医药大学第二附属医院,湖南长沙410005

出　　处：《中医临床研究》2015年第5期1-3,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察补气化痰活血方对进展性缺血性卒中(PIS)患者头部CT缺血灶的影响。方法:54例PIS患者随机分为治疗组和对照组,每组各27例。在一般治疗的基础上,治疗组予补气化痰活血方中药汤剂口服。分别于入院时、入院后每天上午7:30,下午17:30各进行一次斯堪的那维亚卒中量表(SSS)评分,共15d。分别于入院时,病情进展停止后24h做头部CT,测责任病灶最大层面的最大直径。结果:入院时对照组SSS评分为(46.97±4.76)分,进展发生后第7d为(21.46±6.82)分,前后比较有显著性差异。治疗组入院时SSS评分为(46.97±4.76)分,进展发生后第7d为(47.83±3.52)分,与入院时比较无显著性差异(P>0.05)。第7d时两组间SSS比较有显著性差异(P<0.01)。对照组入院时缺血灶直径为(6.03±2.24)mm,第7d时为(26.35±11.26)mm,治疗组入院时直径为(6.25±2.37)mm,第7d时为(15.12±6.33)mm,两组间比较有显著性差异(P<0.01)。结论:以白参为主药的补气化痰活血方可有效阻止缺血性卒中病情进展,其机理可能与阻止缺血灶扩展有关。Objective：To observe clinical efficacy of Buqi Huatan Huoxue recipe on on head CT ischemic focus in patients with progressive ischemic stroke. Methods：54 patients were randomly divided into the treatment group （27 cases） and the control group （27 cases）. The treatment group was given Buqi Huatan Huoxue decoction on the basis of conventional treatment. SSS scores were tested at 7：30 and 17：30 after hospitalization, for 15d. Head CT was tested on admission and after 24h after stopping of progression. The largest diameter of head CT ischemic focus was measured. Results：In control group, SSS score was （46.97±4.76） on admission, （21.46±6.82） in 7th d;the difference was statistically significant （P〈0.05）. In treatment group, SSS score was （46.97±4.76） on admission, （47.83±3.52） in 7th d;the difference showed no statistically significant （P〉0.05）. In 7th d, the difference in both was statistically significant （P〈0.01）. In control group, the diameter of head CT ischemic focus was （6.03±2.24）mm, （26.35±11.26）mm in 7th d;in treatment group, the diameter of head CT ischemic focus was （6.25±2.37） mm, （15.12±6.33） mm in 7th d;the difference was statistically significant （P〈0.01）. Conclusion：Buqi Huatan Huoxue recipe could effectively prevent the progression. The mechanism may be related to prevention of expandingischemic lesions.

关 键 词：补气化痰活血 进展性缺血性卒中 缺血灶 

分 类 号：R743.33[医药卫生—神经病学与精神病学]