甜草总多酚体外抗氧化活性研究  

Antioxidant Activity in vitro of Total Polyphenol from Oldenlandia cantonensis How

作　　者：苟体忠[1,2] 雷小朋[3] 徐绍琴 孙大方[1] 陈永婷[1] 彭章美 

机构地区：[1]凯里学院化学与材料工程学院,贵州凯里556011 [2]凯里学院应用化学研究所,贵州凯里556011 [3]凯里学院人事处,贵州凯里556011 [4]凯里学院继续教育学院,贵州凯里556011

出　　处：《湖北农业科学》2015年第4期947-949,共3页Hubei Agricultural Sciences

基　　金：贵州省科学技术厅自然科学基金项目[黔科合J字(2011)2079号];凯里学院博士专项基金;贵州省高校优秀科技创新人才计划项目[黔教合KY字(2012)099号];贵州省教育厅高层次人才引进项目(院科通(2012)7号);凯里学院重点项目(Z1202);贵州省特色重点学科资助项目[黔教高发(2011)208号];凯里学院重点学科资助项目[院通字(2010)86号]

摘　　要：采用总抗氧化能力、OH·清除率、DPPH·清除率来考察甜草(Oldenlandia cantonensis How)总多酚的体外抗氧化活性。结果表明,甜草总多酚总抗氧化能力略小于维生素C(VC),但甜草总多酚OH·清除率远高于VC。此外,甜草总多酚对DPPH·的IC50(22.2μg/m L)与VC相近(16.0μg/m L)。甜草总多酚是天然的抗氧化活性剂和自由基清除剂。The antioxidant activity in vitro of total polyphenol from Oldenlandia cantonensis How was evaluated by total antiox- idant activity,hydroxyl and DPPH free radical scavenging effect. The results showed that the total antioxidant activity of total polyphenol from Oldenlandia cantonensis How was slightly less than that of VC. The hydroxyl free radical scavenging effect of total polyphenol from Oldenlandia cantonensis How was much higher than that of VC. The half-maximal inhibitory concentra- tion （ICso） for DPPH free radicals of total polyphenol from Oldenlandia cantonensis How and VC was similar,which was 22.2 Ixg/mL and 16.0 I^g/mL,respectively. It is indicated that total polyphenol from Oldenlandia cantonensis How was an effective and natural antioxidant, and free radical scavenger.

关 键 词：甜草(Oldenlandia cantonensis How) 总多酚 抗氧化活性 OH·清除率 DPPH·清除率 

分 类 号：R961[医药卫生—药理学] S567.21[医药卫生—药学]