抗震止痉胶囊联合谷胱甘肽治疗帕金森病剂末现象观察  被引量:5

Clinical Observation on Combination therapy of Kangzhen Zhijing Capsule and Glutathione for Treatment of Parkinson Patients with End-of-dose Phenomenon

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作  者:陈怀珍[1] 徐国存[1] 方向[1] 李俊[1] 葛青[1] 张静[1] 吴云虎[1] 李良勇[1] 王萍[1] 

机构地区:[1]安徽中医药大学第一附属医院脑病中心,安徽合肥230031

出  处:《中医药临床杂志》2015年第2期187-189,共3页Clinical Journal of Traditional Chinese Medicine

基  金:国家临床重点专科基金资助(2100202)

摘  要:目的:观察中药抗震止痉胶囊联合谷胱甘肽治疗帕金森病剂末现象的临床疗效。方法:选取42例出现剂末现象的帕金森病患者,加用抗震止痉胶囊和谷胱甘肽治疗4周。结果:治疗后Webster评分、UPDRSII\III评分均有改善,WOQ-9问卷的运动与非运动症状改善。结论:中药抗震止痉胶囊联合谷胱甘肽能显著改善帕金森病的剂末现象。Objective:To observe the combination therapy of Kangzhen Zhijing capsule and glutathione on Parkinson patients with end-of-dose phenomenon. Methods: 42 Parkinson patients with end-of-dose phenomenon were treated with the com- bination therapy of Kangzhen Zhijing capsule and glutathione for 4 weeks. Results: The UPDRS Ⅱ / Ⅲ scores, Webster score, and Motor symptoms and non-motor symptoms in Wearing-off Questionnaire significantly improved after treatment. Conclusion: The combination therapy of Kangzhen Zhijing capsule and glutathione treatment can significantly improve the end-of-dose phenomenon in Parkinson patient.

关 键 词:帕金森病 抗震止痉胶囊 还原型谷胱甘肽 剂末现象 

分 类 号:R742.5[医药卫生—神经病学与精神病学]

 

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