血清及胸液C-反应蛋白对胸腔积液病因诊断的研究  

Value of combined detection of CRP in serum and pleural effusion in the etiological diagnosis of pleural effusion

作　　者：茅敏华[1] 张金松[1] 姜觉如[1] 

机构地区：[1]启东市人民医院呼吸内科,江苏启东226200

出　　处：《临床肺科杂志》2015年第6期1019-1021,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨血清及胸液C-反应蛋白(CRP)对类肺炎性胸腔积液、结核性胸腔积液和癌性胸腔积液的价值。方法选取胸腔积液患者80例,其中类肺炎性胸腔积液35例,结核性胸腔积液13例,恶性胸腔积液32例,比较所有患者血清和胸液中CRP的测量值。结果类肺炎性胸腔积液血清及胸液中CRP含量显著高于结核性胸腔积液,差异有统计学意义(P<0.05);结核性胸腔积液血清及胸液中CRP含量显著高于癌性胸腔积液,差异有统计学意义(P<0.05)。结论血清和胸液中CRP对胸腔积液病因诊断具有一定的临床价值;可以作为良恶性胸腔积液鉴别诊断的参考指标。Objective To study the diagnostic value of combined detection of C-reactive protein （ CRP） in both serum and pleural effusion in the diagnosis of parapneumonic effusion, tuberculosis pleuritis and malignant pleural effusion. Methods The study selected 80 patients with pleural effusion to detect and compare the results of CRP in serum and pleural effusion, including 35 patients with parapneumonic effusion, 13 patients with tuberculosis pleuritis, and 32 patients with malignant pleural effusions. Results The levels of CRP in serum and pleural effusion were significantly higher in parapneumonic effusion than in tuberculosis pleuritis （P〈0. 05）, and they were significantly higher in tuberculosis pleuritis in malignant pleural effusion （ P〈0. 05 ） . Conclusion The combined detection of CRP in serum and pleural effusion has great diagnostic value and can be an useful indicator in the differential diagnosis of benign and malignant pleural effusion.

关 键 词：C-反应蛋白 胸腔积液 病因诊断 

分 类 号：R730.43[医药卫生—肿瘤]