丹参多酚酸对急性缺血性脑卒中的疗效分析  

The curative effect analysis of salvianolate in acute ischemic stroke

作　　者：侯兴旺[1] 王颖慧[1] 

机构地区：[1]包头医学院第一附属医院神经内一科,内蒙古包头014010

出　　处：《中国现代医生》2015年第10期100-102,共3页China Modern Doctor

基　　金："十二五"国家科技重大专项(2012zx09101202)

摘　　要：目的研究丹参多酚酸对急性缺血性脑卒中的临床疗效。方法选取急性缺血性脑卒中患者200例,并随机分为观察组和对照组各100例。对照组采用内科常规治疗,观察组在常规治疗的基础上给予注射用丹参多酚酸治疗,两组均以14 d为1个疗程,观察患者的临床疗效、神经功能缺损情况、日常生活能力,比较两组治疗后效果。结果 (1)观察组基本治愈14例,显著进步46例,进步31例,无效8例,加重1例,总有效率为91%,其总有效率显著高于对照组的75%(P<0.05)。(2)治疗后观察组的CNIHSS评分神经功能缺损情况和Barthel指数患者的日常生活能力改善程度显著优于对照组(P<0.05)。结论注射用丹参多酚酸对急性缺血性脑卒中有较好的疗效,可显著改善患者的神经功能缺损情况,提高患者的日常生活能力,且能显著改善急性缺血性脑卒中的微循环,增加脑部血液供应,保护脑细胞。Objective To study the clinical efficacy of salvianolate in acute ischemic stroke. Methods A total of 200 cases of acute ischemic stroke patients were chosen and randomly divided into the control group with 100 cases and the observation group with 100 cases. The control group received internal routine treatment, and the observation group received salvianolate treatment on the basis of routine treatment, both for 14 days as a course of treatment. Clinical ef-ficacies, neurological deficits and the daily life abilities of all the patients in the two groups after treatment were ob-served and compared. Results （1） 14 cases in the observation group were cured basically, 46 cases improved significantly, 31 cases improved, 8 cases were ineffective and one case aggravated. The total effective rate in the observation group was 91%, significantly higher than 75% in the control group （P〈0.05）. （2） Neurological deficits measured by CNIHSS score and the daily life abilities of patients measured by Barthel index in the observation group after treatment im-proved significantly better than those in the control group （P〈0.05）. Conclusion Salvianolate has a good effect in cur-ing acute ischemic stroke, and it can significantly improve the patients＇ neurological deficits and daily life abilities, salvianolate can significantly improve the microcirculation in acute ischemic stroke, increase blood supply to the brain and protect brain cells.

关 键 词：急性缺血性脑卒中 丹参多酚酸 神经功能 

分 类 号：R743.72[医药卫生—神经病学与精神病学] R741[医药卫生—临床医学]