宫颈原始神经外胚叶肿瘤  

Primitive neuroectodermal tumors of the cervix uteri

作　　者：雷呈志[1] 

机构地区：[1]中国医学科学院肿瘤医院妇科,北京100021

出　　处：《中华妇幼临床医学杂志（电子版）》2015年第2期18-22,共5页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

摘　　要：原始神经外胚叶肿瘤(PNET)是一类罕见的高度恶性肿瘤,多发生于儿童和青少年。世界卫生组织(WHO)将其分为中枢型PNET(cPNET)和外周型PNET(pPNET)。pPNET多发生于软组织、骨、腹膜后等部位,发生于宫颈的PNET十分罕见。目前文献报道的宫颈PNET病例很少,笔者拟通过复习文献,探讨宫颈PNET的临床病理学特点及其治疗与预后。宫颈PNET的临床诊治不同于宫颈鳞癌(SCC)和宫颈腺癌,目前对其主要采用化疗、手术和放疗结合的综合治疗措施。Primary primitive neuroectodermal tumors （PNET） are rare and high-grade malignant tumors that mostly occur in children and young adults. PNET are divided into central-type PNET （cPNET） and peripheral-type PNET （pPNET） by the World Health Organization （WHO）. pPNET majorly occur in soft tissues, skeleton, retroperitoneum and so on. pPNET of the cervix uteri is extremely rare. To date, few eases of pPNET of the cervix uteri have been reported in literature, and data on long term follow-up are not available. We focus on clinicopathologic profile, treatment, and clinical outcomes of patients with pPNET of cervix uteri by literatures review. Treatment strategies of pPNET of cervix uteri should be different from squamous carcinoma of the cervix （SCC） and adenocarcinoma of the cervix. Multimodality therapies including Surgery, chemotherapy, radiotherapy and other treatment may prolong survival of patients of pPNET of cervix unteri.

关 键 词：神经外胚瘤 原始神经外胚叶肿瘤 宫颈癌 肿瘤治疗方案 

分 类 号：R737.33[医药卫生—肿瘤]