非酒精性脂肪肝临床危险因素相关性研究  

Study on the correlation between the clinical risk factors of nonalcoholic fatty liver disease

作　　者：王晓文[1] 李玉玲[1] 

机构地区：[1]民航总医院感染疾病科,北京100123

出　　处：《中国医刊》2015年第4期73-75,共3页Chinese Journal of Medicine

摘　　要：目的探讨非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)相关临床危险因素。方法随机选取NAFLD患者共98例为病例组,另外随机选取健康者80例作为对照组。检查两组体重指数、血脂、血尿酸、血红蛋白和肝功能,然后对比分析两组研究对象的检测结果。观察NAFLD与所检查项目的相关性。结果病例组中体重指数、血脂异常、高尿酸血症、高血红蛋白和肝功能异常发生率均高于对照组(P<0.05)。Logistic回归分析显示,NAFLD与体重指数、血脂异常、高尿酸血症和高血红蛋白呈显著相关。结论 NAFLD患者应加强对肥胖、血脂异常、高尿酸血症和高血红蛋白危险因素的检测,为NAFLD病因病机的探讨提供临床依据,从而达到积极防治NAFLD的目的。Objective Discussion on nonalcoholic fatty liver disease （ NAFLD） related clinical risk factors. Method Randomly selected in 2011 January-2014 year in January in diseases of the infection in our hospital of nonalcoholic fatty liver disease in patients with clinical cases of 98 patients and 80 healthy subjects as the research object,body mass index,serum lipid,uric acid,hemoglobin and liver function were investigated in two groups. Then test results of two groups were comparative analysis. At the same time,nonalcoholic fatty liver and the detection item correlation was observed. Result In the case group, obesity, abnormal blood lipid, hyperuricemia, high hemoglobinand liver function abnormal rate was higher than that of control group（P〈0. 05）. Logistic regression analysis showed that, NAFLD was significantly related to body mass index, abnormal blood lipid, hyperuricemia and high hemoglobin. Conclusion NAFLD patients should strengthen the inspection of obesity,dyslipidemia,hyperuricemia,high hemoglo-bin and other risk factors,to provide the clinic basis for the study of NAFLD pathogenesis,and to achieve the active prevention and treatment of NAFLD objective.

关 键 词：非酒精性脂肪性肝病 血脂代谢 代谢综合征 胰岛素抵抗 

分 类 号：R575[医药卫生—消化系统]