度洛西汀治疗高龄帕金森病患者疼痛的疗效分析  

Clinical Observation on Duloxetine for Treatment of Pain in Very Old Patients with Parkinson's Disease

作　　者：孙虹[1] 管锦群[1] 王婷[1] 杨扬[1] 王珊珊[1] 贾建军[1] 管维平[1] 王振福[1] 

机构地区：[1]中国人民解放军总医院,北京100853

出　　处：《中西医结合心脑血管病杂志》2015年第4期469-470,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的观察度洛西汀治疗帕金森病患者疼痛的疗效。方法采用非对照开放式实验研究方法,以20例高龄合并帕金森疼痛的患者为研究对象,给予度洛西汀每日60 mg顿服,治疗12周,评价药物的安全性和有效性。结果经过度洛西汀治疗4周后,高龄帕金森病患者疼痛和生活质量得到明显改善,运动功能无恶化,安全评价好。结论度洛西汀可以安全有效地改善高龄帕金森患者的疼痛症状,改善患者生活质量。Objective To observe the effects of duloxetine for treatment of pain in very old patients with Parkinson’s disease （PD）. Methods Twenty very old patients with PD were treated with duloxetine 60 mg once daily for 12 weeks.The efficacy,tolerability and safety were evaluated.Results The pain and quality of life in patients with PD were improved.No worsening of movement function was observed.Conclusion Duloxetine is effective in the treatment of pain in patients with PD,and has good toleration.

关 键 词：帕金森病 疼痛 度洛西汀 

分 类 号：R742.5[医药卫生—神经病学与精神病学]