机构地区:[1]民航总医院消化内科,北京100123 [2]民航总医院心内科,北京100123 [3]民航总医院麻醉科,北京100123
出 处:《中国医药》2015年第5期658-660,共3页China Medicine
基 金:首都临床特色应用研究专项课题(Z141107002514139)
摘 要:目的 探讨无痛胃镜、结肠镜联合检查用于高血压患者的安全性.方法 纳入2012年1月至2014年7月于民航总医院接受胃镜、结肠镜联合检查的高血压患者160例,完全随机分为对照组和研究组,各80例.对照组接受普通胃镜、结肠镜检查;研究组于地佐辛联合丙泊酚麻醉下接受无痛胃镜、结肠镜联合检查观察2组检查前后血压、心率、脉搏血氧饱和度(SpO2)的变化,比较2组检查时间差异,并观察和评估检查过程中和检查结束后2组患者不良反应、疼痛视觉模拟量表(VAS)评分及患者满意率.结果 2组患者均顺利完成检查.研究组检查过程中收缩压、舒张压、心率、SpO2与检查前比较,差异均无统计学意义[(142±10) mmHg(1 mmHg=0.133 kPa)比(150±15) mmHg,(89±10) mmHg比(90±9)mmHg,(75±8)次/min比(79±10)次/min,(96.2±1.6)%比(98.1±1.5)%;均P>0.05];对照组检查过程中收缩压和心率明显高于检查前[(159±11)mmHg比(147±15) mmHg,(97±15)次/min比(77±9)次/min;p<0.05] 研究组胃镜和结肠镜检查时间均明显短于对照组,差异有统计学意义[(7.9±3.1)min比(11.1±2.6)min,(4.9 ±0.5)min比(9.1 ±1.7)min;均P<0.05].研究组在检查过程中呛咳、恶心和呕吐发生率低于对照组[13.8%(11/80)比47.5%(38/80),6.3%(5/80)比51.3%(41/80)],术后VAS评分低于对照组[(2.3±0.7)分比(3.1±0.9)分],患者满意率高于对照组[97.5%(78/80)比76.3% (61/80)],差异均有统计学意义(均P<0.05).结论 高血压患者行无痛胃镜、结肠镜联合检查安全,效果好.Objective To investigate the safety of painless gastroscopy-colonoscopy examination in the hypertension patients.Methods Totally 160 hypertension patients from January 2012 to July 2014 were divided into study group (80 cases) receiving painless gastroscopy-colonoscopy combined examination under anaesthesia with dezocine and propofol,and control group (80 cases) receiving common gastroscopy-colonoscopy.The changes of blood pressure,heart rate (HR) and peripheral oxygen saturation (SpO2) during and after gastroscopy-colonoscopy were observed;the examination time and visual analog scales (VAS) after examination and side effects were compared between the two groups.Results The patients in both the two groups successfully completed the inspection.During the gastroscopy-colonoscopy,no statistical changes of systolic pressure,diastolic pressure,HR and SpO2 were observed in study group [(142 ± 10) mmHg vs (150 ± 15) mmHg,(89 ± 10) mmHg vs (90 ± 9) mmHg,(75 ± 8) times/min vs (79 ± 10) times/min,(96.2 ± 1.6) % vs (98.1 ± 1.5) %,all P > 0.05];while the systolic pressure and HR were obviously increased in control group [(159 ± 11) mmHg vs (147 ± 15) mmHg,(97 ± 15) times/min vs (77 ± 9) times/min,both P < 0.05].The time of gastroscopy and colonosropy was both shorter in study group compared with that in control group [(7.9 ±3.1) min vs (11.1 ±2.6) min,(4.9 ± 0.5) min vs (9.1 ± 1.7) min,both P < 0.05].The incidence of bucking,the incidence of nausea and vomiting,the VAS score were lower,and the satisfaction rate of patients was higher in study group than those in control group [13.8 (11/80) vs 47.5 (38/80),6.3 (5/80) vs 51.3 (41/80),(2.3 ±0.7) scores vs (3.1 ± 0.9) scores,97.5 (78/80) vs 76.3 % (61/80)] (all P < 0.05).Conclusion Painless gastroscopy-colonoscopy examination is safe and effective in hypertensive patients.
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