90岁以上高龄缺血性脑卒中患者颅内外动脉硬化研究  

Study on intracranial and extracranial arteriosclerosis in ischemic stroke elderly patients aged over 90 years

作　　者：王峻峰[1] 郁可[1] 钟婷婷[1] 周华东[1] 

机构地区：[1]第三军医大学大坪医院野战外科研究所神经内科,重庆400042

出　　处：《重庆医学》2015年第13期1774-1776,共3页Chongqing medicine

摘　　要：目的探讨90岁以上高龄缺血性脑卒中患者颅内外动脉硬化的分布特点及相关危险因素。方法连续回顾2009年7月至2014年7月在该院住院诊断为缺血性卒中且已行头颈部CT血管造影(CTA)检查的患者。年龄大于或等于90岁者设为研究组,年龄小于90岁者设为对照组,比较两组CTA影像形态学特点及差异,分析两组患者既往病史、体质量指数、血压、血糖、尿酸、血脂等危险因素与颅内外动脉硬化发生的关系。结果研究组的颅内外动脉狭窄、斑块发生率均显著高于对照组(P<0.01)。研究组中既往有高血压、冠心病病史者多于对照组(P<0.05),收缩压、舒张压水平也高于对照组(P<0.05)。结论 90岁以上高龄缺血性脑卒中患者的颅内外动脉硬化严重程度及发生率均明显增加。Objective To investigate the distribution characteristics and risk factors of intracranial and extracranial arteriosclerosis in ischemic stroke elderly patients aged over 90 years. Methods The inpatients with diagnosed ischemic stroke and brain CTA scanning in our hospital from July 1,2009 to July 1,2014 were consecutively enrolled in this study. The subjects were divide into the study group （≥90 years,n= 92） and the control group （〈 90 years, n= 110）. The morphological characteristics of CTA images and differences were compared between the two groups,the association between intracranial and extracranial arteriosclerosis with the past medical history, body mass index （BMI）, blood pressure, blood glucose, blood lipid and uric acid was analyzed. Results The frequency of intracranial and extracranial atherosclerotic stenosis and plaques in the study group was significantly higher than that in the control group （P〈0.01）. The patients number of past hypertension history and coronary disease in the study group was greater than that in the control group （P〈0.05） ,so did the level of systolic or diastolic blood pressure. Conclusion The prevalence and severity of intracranial and extracranial arteriosclerosis are obviously increased in the ischemic stroke elderly patients aged 90 over years.

关 键 词：动脉硬化 CT血管造影 90岁以上 

分 类 号：R743.31[医药卫生—神经病学与精神病学]