羚羊钩藤汤临证加减治疗高龄脑出血患者临床研究  

Clinical studies of antelope Uncaria soup for elderly patients with cerebral hemorrhage

作　　者：焦健[1] 徐淑娜[1] 

机构地区：[1]山东莱芜市人民医院药剂科,莱芜271199

出　　处：《中国实用神经疾病杂志》2015年第7期21-23,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析羚羊钩藤汤临证加减治疗高龄脑出血患者的临床疗效。方法选取我科2012-01—2014-01因急性脑出血入院治疗的高龄患者102例,随机分为实验组和对照组。对照组予以西医内科治疗,实验组在对照组基础上,加用羚羊钩藤汤临证加减。对比2组患者治疗前和治疗7天后的头颅CT血肿、水肿体积;对比2组患者治疗前及治疗后不同时间点的NIHSS评分、PRO量表、Barthel量表和改良Rankin量表评分。对比2组患者治疗3个月后的临床疗效。结果 2组患者治疗7d后头颅CT血肿和水肿体积均显著小于治疗前,P<0.05;实验组治疗7d后头颅CT血肿和水肿体积均显著小于对照组,P<0.05。2组治疗7d、14d、21d和3个月后NIHSS评分均逐渐显著下降,P<0.05;实验组治疗7d、14d、21d和3个月后NIHSS评分均显著低于同期对照组,P<0.05。2组患者治疗3个月后PRO量表总分和改良Rankin量表评分显著低于治疗前,Barthel量表评分显著高于治疗前,P<0.05;实验组治疗3个月后PRO量表总分和改良Rankin量表评分显著低于对照组,Barthel量表评分显著高于对照组,P<0.05。2组总有效率差异无统计学意义(P>0.05);但实验组基本痊愈+显著进步率显著高于对照组,P<0.05。结论在西医治疗基础上,加用羚羊钩藤汤临证加减治疗高龄脑出血可有效清除颅内血肿,改善患者生活质量,临床疗效显著。Objective To analyze the clinical efficacy of antelope uncaria soup in old patients with cerebral hemor‐rhage.Methods 102 hospitalized elderly patients in our department from January 2012 to January 2014 for the treatment of a‐cute cerebral hemorrhage were randomly divided into experimental and control groups. Control group received Western medicine treatment ;the experimental group received uncaria soup plus antelope clinical subtraction based on the control group. The head CT hematoma ,edema volume were compared in two groups of patients before treatment and 7 days after treatment. NIHSS score ,PRO Scale ,Barthel scale and the modified Rankin Scale score before and after treatment at different time points were compared in two groups of patients. The clinical efficacy of three months after treatment was compared between the two groups.Results The cranial CT hematoma and edema volumes in two groups of patients 7 days after treatment were signifi‐cantly lower than those before treatment , P〈0.05. The cranial CT hematoma and edema volumes in experimental treatment group 7 days after treatment were significantly lower than the control group ,P〈0.05. The NIHSS scores in two groups of pa‐tients 7 days ,14 days ,21 days and three months after treatment were gradually decreased significantly ,P〈0.05. The NIHSS scores in experimental treatment group 7 days ,14 days ,21 days and 3 months after treatment were significantly lower than the same period in the control group ,P〈0.05. The PRO total score and modified Rankin scale score in two groups of patients af‐ter 3 months of treatment were significantly lower than those before treatment ,Barthel scores were significantly higher than those before treatment ,P〈0.05. The PRO total score and modified Rankin scale score in experimental group after treatment of 3 months were significantly lower than the control group ,Barthel scores were significantly higher ,P〈0.05. The total effi‐ ciency of the two groups had no significant difference , P〉 0.05 ;but re

关 键 词：羚羊钩藤汤 临证加减 高龄 脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]