我院306例药品不良反应报告分析  

Analysis on 306 ADR Reports in Our Hospital

作　　者：史涛[1] 林珍[1] 蒋娟[1] 常花蕾[1] 陈雨丹 

机构地区：[1]解放军第174医院药剂科,福建厦门361003

出　　处：《中国药师》2015年第5期829-832,共4页China Pharmacist

摘　　要：目的：了解我院药品不良反应（ ADR）发生的特点及规律。方法：回顾性分析我院2013年收集的306例药品不良反应报告,对患者性别、年龄、给药途径、药物类别、ADR累及系统/器官和临床表现、分类情况、因果关系评价以及报告人员构成比等进行统计分析。结果：306例ADR报告中,51~60岁患者发生ADR例数构成比最高（20.26%）；给药途径以静脉滴注引起的ADR例数构成比最高（65.58%）；药品类别以抗菌药引起的ADR例数构成比最高（20.78%）；ADR累及系统以消化系统为主,占23.91%；医师报告的数量最多,占97.71%。结论：我院应加强对ADR的监测和报告,促进临床合理用药,降低ADR风险,保障患者用药安全。Objective：To study the regularity and characteristics of adverse drug reaction （ ADR） in our hospital. Methods： A retrospective analysis was conducted on 306 ADR reports collected in our hospital in 2013. The reports were statistically analyzed in re-spect of sex, age, route of drug administration, drug categories, organs/systems involved in ADR and clinical manifestations, classifi-cation of ADR, causality assessment, constituent ratio of the reporters etc. Results：In the 306 ADR reports, the incidence of ADR be-tween the age of 51 and 60 was the highest （20. 26%）; the ratio of the ADR induced by intravenously drip administration was the highest in respect of the route of administrations （65. 58%）;the radio of ADR induced by antibacterial agents was the highest in re-spect of drug types （20. 78%）;digestive system was the maln lesion in ADR cases （23. 91%）. The ADR cases were mostly reported by doctors （97. 71%）. Conclusion：Our hospital should enhance the ADR monitoring and reporting, promote the clinical rational drug use, reduce or avoid the risk of ADR and protect medication safety of patients.

关 键 词：药品不良反应 监测 报告 药物警戒 

分 类 号：R97[医药卫生—药品]