血清总胆汁酸测定在肝脏疾病中的应用  

Application of serum total bile acid detection in hepatic disease

作　　者：查长森[1] 

机构地区：[1]广东省佛山市南海区第七人民医院,528247

出　　处：《中国实用医药》2015年第12期42-44,共3页China Practical Medicine

摘　　要：目的探讨血清总胆汁酸(TBA)在各类型肝脏疾病中的应用价值。方法采用循环酶法和速率法测定100例本院健康职工(对照组)和182例肝病患者血清TBA及常用肝功能指标。结果对照组的TBA为(3.9±2.9)μmol/L,各类型肝脏疾病均较对照组高(P<0.01),TBA和常用肝功能检测指标在不同类型肝脏疾病中的测定值的阳性率各有所不同,特别是肝癌和肝硬化在其他酶学指标不高时TBA阳性率分别达到96.0%和89.3%。结论 TBA测定是一个敏感的肝功能检测指标,能反映肝实质损伤,与各酶学指标比较,特别适用于各类型肝脏疾病诊断、疗效观察。Objective To investigate the application value of serum total bile acid （TBA） detection in 〈br〉 hepatic disease.Methods Enzymatic cycling assay and velocity method were applied for detection of serum TBA and common liver function index in 100 healthy staff （control group） and 182 patients with hepatic disease. Results TBA in the control group was （3.9±2.9）μmol/L, and hepatic diseases were all higher than control group （P〈0.01）. TBA and common liver function index had different positive rate in detection of different hepatic diseases, especially for liver cancer and liver cirrhosis with TBA positive rate as 96.0% and 89.3%.Conclusion TBA detection is a sensitive liver function index, and it can show live damage. Compared with enzymology index, it is suitable for diagnosis and effect observation in hepatic disease.

关 键 词：总胆汁酸 肝脏疾病 

分 类 号：R575[医药卫生—消化系统]