Norepinephrine transporter (NET) is expressed in cardiac sympathetic ganglia of adult rat  

作　　者：LiH MaSK 

机构地区：[1]InstituteofBiochemistryandCellBiology,ShanghaiInstitutesforBiologicalSciences,ChineseAcademyofSciences,Shanghai200031,China [2]InstituteofBiochemistryandCellBiology,ShanghaiInstitutesforBiologicalScience

出　　处：《Cell Research》2001年第4期317-320,共4页细胞研究（英文版）

摘　　要：The sympathetic nervous system plays a cardinal role in regulating cardiac function through releasing the neurotransmitter norepinephrine (NE). In comparison with central nervous system, the molecular mechanism of NE uptake in myocardium is not clear. In present study, we proved that in rat the CNS type of NE transporter (NET) was also expressed in middle cervical-stellate ganglion complex (MC-SG complex) which is considered to control the activity of heart, but not expressed in myocardium. The results also showed that NET expression level in right ganglion was significantly higher than in the left, rendering the greater capacity of NE uptake in right ventricle, a fact which may contribute to the maintenance of right ventricular function under pathologic state.

关 键 词：Animals Heart Male MYOCARDIUM Norepinephrine Plasma Membrane Transport Proteins RNA  Messenger RATS Rats  Sprague-Dawley Research Support  Non-U.S. Gov't Stellate Ganglion Symporters 

分 类 号：R331.31[医药卫生—人体生理学]