MYOCARDIUM

作品数：251被引量：642H指数：13
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相关领域：医药卫生更多>>
相关作者：张雪梅杨申张翼周兆年江明性更多>>
相关机构：华中科技大学武汉大学哈尔滨医科大学上海医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金湖北省自然科学基金更多>>
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Electrothermal analysis of radiofrequency tissue ablation with flexible electrodes on large-curvature myocardium surfaces
《Applied Mathematics and Mechanics(English Edition)》2025年第3期573-590,共18页Jiayun CHEN Bochuan JIANG Qi ZHAO Yuhang LI Yafei YIN Xuanqing FAN 
Project supported by the National Natural Science Foundation of China(Nos.U23A20111 and 12372160)。
Radiofrequency ablation(RFA)is a form of minimally invasive procedure that precisely ablates abnormal lesions or hyperplastic tissues through thermal energy generated by the radiofrequency current at the tip electrode...
关键词：radiofrequency ablation(RFA) electrothermal analysis large curvature flexible electrode 
Construction of millimeter-scale vascularized engineered myocardial tissue using a mixed gel
《Regenerative Biomaterials》2024年第3期56-67,共12页Ming Ke Wenhui Xu Yansha Hao Feiyang Zheng Guanyuan Yang Yonghong Fan Fangfang Wang Zhiqiang Nie Chuhong Zhu 
Key projects of the National Natural Science Foundation of China(81830055,82230073);the Postdoctoral Research Special Support Projects of Chongqing(2020-2010010006263477);Thanks for the support of Yonghong Fan's the Science and Technology Innovation Enhancement Projects of Third Military Medical University(2020xQN03).
Engineering myocardium has shown great clinal potential for repairing permanent myocardial injury.However,the lack of perfusing blood vessels and difficulties in preparing a thick-engineered myocardium result in its l...
关键词：engineered myocardium vascularized hiPSC-CM HUVEC FIBRIN 
Fulminant myocarditis induced by SARS-CoV-2 infection without severe lung involvement:insights into COvID-19 pathogenesis
《Journal of Genetics and Genomics》2024年第6期608-616,共9页Han Du Zhongtao Du Liang Wang Hong Wang Mingjun Jia Chunge Zhang Yun Liu Cheng Zhang Ya Zhang Ruifeng Zhang Shuang Zhang Ning Zhang Zhenghai Ma Chen Chen Wenjun Liu Hui Zeng George F.Gao Xiaotong Hou Yuhai Bi 
supported by the National Key R&D Program of China(2023YFC2307500 and 2021YFC2701700);National Natural Science Foundation of China(82341115);Beijing Research Center for Respiratory Infectious Diseases(BJRID2024-003);Major Project of Guangzhou National Laboratory(GZNL2023A01001 and SRPG22-001);the National Science and Technology Infrastructure of China(National Pathogen Resource Center-NPRC-32);Y.B.is supported by the Youth Innovation Promotion Association of CAs(Y2021034);CAS Project for Young Scientists in Basic Research(YSBR-086);the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202208).
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection often leads to pulmonary complications.Cardiovascular sequelae,including myocarditis and heart failure,have also been reported.Here,the study presen...
关键词：COVID-19 SARS-CoV-2 Fulminant myocarditis MYOCARDIUM INFECTION 
Subclinical impairment of left ventricular myocardium function in type 2 diabetes mellitus patients with or without hypertension
《World Journal of Diabetes》2024年第6期1272-1279,共8页Zeng-Guang Chen Guang-An Li Jun Huang Li Fan 
Supported by the Science and Technology Project of Changzhou Health Commission,No.ZD202342.
BACKGROUND Cardiovascular disease has been the leading cause of morbidity and mortality for type 2 diabetes mellitus(T2DM)patients over the last decade.AIM To determine whether layer-specific global longitudinal strai...
关键词：Type 2 diabetes mellitus HYPERTENSION Speckle tracking echocardiography Global longitudinal strain Peak strain dispersion 
Two new phenolic amides from Allium chinense
《Chinese Herbal Medicines》2023年第4期603-606,共4页Xiaoqing Li Shikai Yan Jihong Lu Rui Wang Xianpeng Ma Xue Xiao Yan Zhang Huizi Jin 
supported by Natural Science Foundation of China (No. 81973191);Shanghai Natural Science Fund (No. 19ZR1428100);project supported by the Department of Science and Technology of Guizhou (No. [2018] 2831);the Horizontal Research Project of Shanghai Jiao Tong University (Nos. SA1700111, SA1700118)。
Objective: To isolate the phenolic amides from the dried bulbs of Allium chinense and investigate their myocardium protective activities.Methods: The chemical constituents were isolated and purified by combining with ...
关键词：alichinemideⅠ alichinemideⅡ Allium chinense 3-indolcarbaldehyde myocardium protective activities phenolic amides 
Danhong Injection Up-Regulates miR-125b in Endothelial Exosomes and Attenuates Apoptosis in Post-Infarction Myocardium被引量：1
《Chinese Journal of Integrative Medicine》2023年第12期1099-1110,共12页LI Si-nai LIU Zi-hao ZHOU Ming-xue LIU Wei-hong LAI Xiao-lei LI Ping ZHANG Lei SHANG Ju-ju QIU Sheng-lei LOU Yan TAN Yu-pei XING Wen-long LIU Hong-xu 
Supported by National Natural Science Foundation of China (No.82174106 and No.81703850)。
Objective:To investigate the involvement of endothelial cells(ECs)-derived exosomes in the antiapoptotic effect of Danhong Injection(DHI)and the mechanism of DHI-induced exosomal protection against postinfarction myoc...
关键词：EXOSOME Danhong Injection Chinese medicine miR-125b myocardial infarction APOPTOSIS 
Porphyromonas gingivalis,a periodontal pathogen,impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion被引量：2
《International Journal of Oral Science》2023年第4期626-639,共14页Yuka Shiheido-Watanabe Yasuhiro Maejima Shun Nakagama Qintao Fan Natsuko Tamura Tetsuo Sasano 
supported by Japan Society for the Promotion of Science (JSPS) KAKENHI Grant-in-Aid for Scientific Research (C) 20K08399 (to Yasuhiro Maejima);KAKENHI 19K18985,Grant-in-Aid for JSPS Fellows;MSD Life Science Foundation;Public Interest Incorporated Foundation (to Yuka Shiheido-Watanabe)
While several previous studies have indicated the link between periodontal disease (PD) and myocardial infarction (MI), theunderlying mechanisms remain unclear. Autophagy, a cellular quality control process that is ac...
关键词：INHIBITING MYOCARDIUM PERIODONTAL 
Predictive value of the proportion of hibernating myocardium in total perfusion defect on reverse remodeling in patients with HFrEF undergoing coronary artery bypass graft
《China Medical Abstracts(Internal Medicine)》2023年第2期93-94,共2页鲁瑶 
Objective To evaluate the predictive value of the proportion of hibernating myocardium(HM)in total perfusion defect(TPD)on reverse left ventricle remodeling(RR)after coronary artery bypass graft(CABG)in patients with ...
关键词：BYPASS MYOCARDIUM PERFUSION 
Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS被引量：3
《Acta Pharmaceutica Sinica B》2023年第1期113-127,共15页Xunxun Wu Lian Liu Qiuling Zheng Hui Ye Hua Yang Haiping Hao Ping Li 
supported by the National Key R&D Program of China(2019YFC1711000);the National Natural Science Foundation of China(No.81421005);the“111”Project(B16046)from the Ministry of Education of China and the State Administration of Foreign Experts Affairs of China。
Ischemic preconditioning(IPC)is a potential intervention known to protect the heart against ischemia/reperfusion injury,but its role in the no-reflow phenomenon that follows reperfusion is unclear.Dihydrotanshinone I(...
关键词：Dihydrotanshinone I Ischemic preconditioning PKM2 GLUTATHIONYLATION Myocardial ischemia ROS Oxidation modification Nuclear translocation 
OSKM-mediated reversible reprogramming of cardiomyocytes regenerates injured myocardium
《Cell Regeneration》2022年第1期55-57,共3页Gregory Farber Jiandong Liu Li Qian 
Cellular reprogramming has rapidly become a promising methodology to generate new cardiomyocytes from non-cardiomyocyte cell types.Using the transient expression of OSKM factors,Chen et al.demonstrate a unique reprogr...
关键词：CARDIOMYOCYTES PROGRAMMING MYOCARDIUM 
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