结直肠间质瘤20例诊治分析  

Diagnosis and treatment analysis of 20 colorectal mesenchymoma cases

作　　者：李福顺[1] 李海[1] 郭希伟[1] 董国民[1] 

机构地区：[1]潍坊市益都中心医院普外二科,262500

出　　处：《中国实用医药》2015年第11期41-43,共3页China Practical Medicine

摘　　要：目的探讨结直肠间质瘤的临床诊断、治疗和预后。方法回顾性分析20例结直肠间质瘤患者的临床资料并加以随访。结果临床表现为消化道出血10例、腹部不适5例、腹部肿块3例,体检发现直肠肿物2例。直肠15例,结肠5例。20例均行手术治疗,诊断为良性2例,交界性1例,恶性17例。免疫组化CD117(+)95%(19/20),CD34(+)80%(16/20)。随访率80%,患者中位生存时间为54个月。结论胃肠道间质瘤(GIST)的最后诊断需依靠病理,结直肠间质瘤仍以外科治疗为主,原则上应行局部完全切除。Objective To investigate clinical diagnosis, treatment and prognosis of colorectal mesenchymoma. Methods A retrospective analysis was made on clinical data of 20 colorectal mesenchymoma patients, and follow-up was applied. Results The clinical manifestations included gastrointestinal hemorrhage in 10 cases, abdominal discomfort in 5 cases, abdominal mass in 3 cases, and 2 cases with rectal mass in physical examination. There were 15 rectum cases and 5 colon cases. All cases underwent operation treatment, and there were 2 benign cases, 1 borderline case, and 17 malignant cases. Immnnohistochemieal CD117 （＋） 95% （19/20）, CD34 （＋） 80% （16/20）. Follow-up rate was 80%, and median survival time was 54 months. Conclusion Pathology should be referred by final diagnosis of gastrointestinal stromal tumor （GIST）. Treatment of eoloreetal mesenchymoma is mainly by surgical method, and local resection is necessary in principle.

关 键 词：间质瘤 结直肠 诊断 治疗 

分 类 号：R735.34[医药卫生—肿瘤]