高同型半胱氨酸血症与脑梗死的相关性分析  

The Associative Analysis of Hyperhomocysteinemia and Cerebral Infarction

作　　者：李朋涛[1] 李慧聪[1] 左金玲[1] 武永强[1] 王晓萍[1] 马丽[1] 

机构地区：[1]中国空空导弹研究院洛阳二〇二医院内科,河南洛阳471000

出　　处：《航空航天医学杂志》2015年第5期529-530,共2页Journal of Aerospace medicine

摘　　要：目的研究高同型半胱氨酸(HCY)血症与脑梗死的相关性。方法分析98例脑梗死患者血清HCY水平,将分析结果与周围社区76例60岁以上健康老人体健测定结果进行比较。结果脑梗死患者合并高同型半胱氨酸血症的人数为61例,占62.22%,60岁以上健康对照人群中合并高同型半胱氨酸血症的人数为7例,占9.21%。两者差异有显著性,P<0.05。结论高同型半胱氨酸血症是脑梗死的一种重要致病因素。Objective To investigate the relationship between the level of plasma homocysteine and cerebral infarc- tion in patients. Methods The level of plasma homocysteine was tested in 98 cerebral infarction patients and 76 age - matched healthy populations. The risk factor was analyzed with Spearman correlation analysis. Results There was 62. 22% cerebral infarction patients suffered from hyperhomocysteinemia, while only 9. 21% healthy group. The level of homocysteinemia in the cerebral infarction group was significantly higher than in healthy group. Spearman correlation a- nalysis showed that hyperhomocysteinemia is a risk factor of cerebral infarction （P 〈 0. 05）. Conclusions The level of plasma homocysteineis associated with the occurance of cerebral infarction. Hyperhomocysteinemia is an independent risk factor for cerebral infraction.

关 键 词：脑梗死 高同型半胱氨酸血症 

分 类 号：R743[医药卫生—神经病学与精神病学]