骨髓间充质干细胞的视网膜保护研究进展  

Research progress on retinal protection of bone marrow mesenchymal stemcells

作　　者：林雯[1,2] 徐国兴[1,2] 

机构地区：[1]福建医科大学附属第一医院眼科 [2]福建省眼科研究所,中国福建省福州市350005

出　　处：《国际眼科杂志》2015年第5期799-802,共4页International Eye Science

基　　金：国家自然科学基金资助项目(No.81271026)~~

摘　　要：骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs)富集于骨髓,可跨胚层分化,是一种具有多向分化潜能的成体干细胞。BMSC易于分离培养,可高效扩增和表达,具有组织修复能力。由于其具有免疫调节能力,能分泌神经营养因子,使BMSC可以作为移植治疗视网膜疾病的种子细胞。本文将对BMSCs的视网膜保护研究进展作一综述。Bone marrow mesenchymal stem cells （ BMSCs ） is a kind of adult stem cells mainly enriched in bone marrow, which possesses multiple differentiation potential and can differentiate into trans-germinal layer. lt is easy for BMSC to be isolated and cultured, which has the ability of repairing various tissues with efficient proliferation and expression. BMSC could be used as seed cell for the transplantation therapy of retinal disease because of its properties of immunoregulation and neurotrophin secretion. This review focuses on research progress on retinal protection of BMSCs.

关 键 词：骨髓间充质干细胞 视网膜 保护 研究进展 

分 类 号：R774.1[医药卫生—眼科]