内镜窄波成像Barrett食管上皮形态变化与病理结果的对照分析  

Contrast analysis of microstructure of esophagus epithelium between pathologic results and narrow band imaging diagnosis

作　　者：周生勇 董新峰[1] 刘军兰[2] 刘志琴[1] 

机构地区：[1]嘉峪关市第一人民医院消化内科,甘肃嘉峪关735100 [2]嘉峪关市第一人民医院病理科,甘肃嘉峪关735100

出　　处：《临床消化病杂志》2015年第2期84-86,共3页Chinese Journal of Clinical Gastroenterology

摘　　要：[目的]探讨内镜窄波成像(NBI)下Barrett食管(BE)上皮形态变化特点与病理组织学诊断结果的符合率。[方法]选取胃镜检查疑诊为BE的102例患者,NBI模式下实时观测BE上皮形态变化特点,判断肠上皮化生类型,随后对所检查部位黏膜靶向活组织病理检查,分析两者诊断结果的相符率。[结果]91例患者被确诊为BE,NBI模式下根据小凹的形态特点分成规则无增粗型、规则增粗型、紊乱增粗型,与之相对应的为胃底腺型、贲门腺型、特殊肠上皮化生型,经靶向活组织病理检查后证实其准确度分别为85.7%、86.6%、88.4%。[结论]NBI可准确分辨BE上皮形态变化的组织类型,靶向活检提高组织病理学准确性,两者诊断符合率达≥85%。[Objective]To investigate relation：between narrow band imaging（NBI）features of Barrett e sophagus（BE）epithelium and results of pathologic diagnosis. [Methods]A total of 102 suspicious patients were included in the study. Pattern changes of BE. epithelium were observed in real time and determined types of intestinal metaplasia. Then the mucosa were investigated by target biopsy. Accuracy of both findings we compared. [Results]A total of 91 patients diagnosed as BE pit patterns were classified into different types under NBI.enlargement of mucosa fold of hypertrophy of gastric pit,gastric pit regular enlargement of mucosa,and gastric pit irregular enlargement of mucosa compared with fundic gland type, cardiac gland type and specialized intestinal metaplasia. Accuracy determined by target biopsy was 85.7G,86.6% and 88.4%. [Conclusion]NBI can distinguish exactly types of BE epithelium changes, target biopsy increased accuracy of pathology,the two methods of diagnose accordance rate is≥85%.

关 键 词：BARRETT食管 内镜窄波成像 肠化生 活组织病理检查 

分 类 号：R735.1[医药卫生—肿瘤]