罗伊乳杆菌LE16益生特性的研究  

Study on the probiotic properties of Lactobacillus reuteri LE16

作　　者：张和春 张旻 杭晓敏 

机构地区：[1]上海交大昂立股份有限公司生物医药研究院,上海200233

出　　处：《中国微生态学杂志》2015年第4期376-378,共3页Chinese Journal of Microecology

基　　金："十二五"农村领域国家科技计划课题项目(2011AA100901-4)

摘　　要：目的研究罗伊乳杆菌LE16的益生特性。方法通过体外和动物实验,评价罗伊乳杆菌LE16的益生特性。结果该菌株对p H 2.5的强酸和0.3%高胆盐环境均有良好的耐受性。对引起肠道感染的几种病原菌均有不同程度的拮抗,尤其对枯草芽胞杆菌、伤寒沙门菌、单核细胞增生李斯特菌及蜡样芽胞杆菌的抑制作用最强。对肠道菌群正常和失调的小鼠均具有调节功能。结论罗伊乳杆菌LE16具有良好的益生性能,可作为益生菌菌株开发应用于食品和保健食品中。Objective To study the probiotic properties of Lactobacillus reuteri LE16. Methods The probiotic properties of Lactobacillus reuteri LE16 were evaluated with in vitro animal experiments. Results Lactobacillus re- uteri LE16 showed high tolerance to pH 2. 5 and 0. 3% oxgall environment. It exhibited a broad inhibitory effect on enteric pathogenic bacteria, especially Bacillus subtilis, Salmonella typhimurlum, Listeria monocytogenes and Bacil- lus cereus. It also had regulatory effect on normal or imbalanced intestinal flora in mice. Conclusion Lactobacil- lus reuteri LE16 shows excellent probiotic properties. It can be developed and used in food and health food as a pro- tiotie strain.

关 键 词：罗伊乳杆菌 益生特性 肠道菌群 

分 类 号：Q935[生物学—微生物学]