定量MRI技术在乳腺癌新辅助化疗疗效评价中的研究现状  

Research Advances in Evaluation of Effect of Quantitative MRI Techniques on Neoadjuvant Chemotherapy for Breast Cancer

作　　者：杨群[1] 何云[1] 任伯绪[1] 

机构地区：[1]长江大学医学院,湖北荆州434023

出　　处：《医学综述》2015年第8期1446-1448,共3页Medical Recapitulate

摘　　要：新辅助化疗已经成为乳腺癌综合治疗的重要组成部分,临床实践中迫切需要一种能准确评价新辅助化疗的方法为临床制订最佳的治疗方案提供依据。近年来,定量磁共振成像技术在早期评价乳腺癌新辅助化疗疗效方面显示出独特的优势。它通过监测肿瘤内一些可量化的参数,可在细胞分子功能水平对经新辅助化疗后肿瘤发生的变化进行客观定量的分析,在肿瘤形态发生改变之前评估乳腺癌新辅助化疗的疗效。因此,定量磁共振成像技术有望成为早期评价乳腺癌新辅助化疗疗效的有效手段。Neoadjuvant chemotherapy has become an important part of comprehensive therapy for breast cancer.An effective evaluation method to monitor the response to neoadjuvant chemotherapy is urgently required in clinic to provide an important reference for clinicians to choose optimal chemotherapy program . Recently,quantitative magnetic resonance imaging techniques has showed unique advantages in evaluating early response to neoadjuvant chemotherapy in patients with breast cancer.It can objectively and quantitatively ana-lyze the changes in tumor at the level of cellular and molecular after neoadjuvant chemotherapy by monitoring quantifiable parameters in tumor so as to early predict the response to neoadjuvant chemotherapy before the tumor morphology changes.Therefore, quantitative magnetic resonance imaging techniques is expected to become an effective means in evaluating the response of breast cancer to neoadjuvant chemotherapy .

关 键 词：乳腺癌 磁共振成像 新辅助化疗 定量分析 

分 类 号：R737.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]