142例青年人胃癌临床病理特征及预后因素分析  

Gastric Cancer in Young Patients-An Analysis of 142 Cases

作　　者：张雯[1] 崔成旭[1] 王金万[1] 

机构地区：[1]中国医学科学院肿瘤医院肿瘤内科

出　　处：《中国医药导刊》2015年第4期325-327,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨35岁以下青年人胃癌的临床病理特征及预后因素。方法:回顾性分析了中国医学科学院肿瘤医院2005年1月至2009年12月收治的142例35岁以下青年人胃癌的临床病理资料。结果:全组共142例,男性63例,占44.3%;女性79例,占55.6%。35岁以下青年人胃癌占同期胃癌病例的3.5%。病理学以低分化腺癌(77%)多见。临床分期以Ⅲ、Ⅳ期占多数(62.2%)。根治手术率为74.6%。全组5年生存率为42%。多因素回归分析表明TNM分期是影响预后的独立因素。结论:青年人胃癌以低分化腺癌占多数,临床分期以Ⅲ、Ⅳ期占多数。影响青年人胃癌预后的主要因素为TNM分期。Objective： To investigate the clinicopathological features of patients younger than 35 years of age with gastric carcinoma.Methods： Clincopathologic data of 142 patients younger than 35 years of age with gastric cancer in our cancer center during a period from January 2005 to December 2009 were reviewed retrospectively.Results： Total 142 patients include 63 of males （44.3%）and 79 of females（55.6%）.The patients younger than 35 years of age accounted for 3.5% of homochronous patients with gastric cancer. Pathologically, there were more poorly differentiated adenocarcinoma （77%） than others.According to TNM classification, 62.2% of all cases were stage Ⅲ/Ⅳ diseases.The curative resection rate was 74.6%.The overall 5-year survival rate was 42%.Multivariate analysis showed that TNM staging of tumor was independent prognostic factor.Conclusion： The clinicopathological characteristics of young patients with gastric cancer indentified in this study include： more carcinomas of poorly differentiated adenocarcinoma and more stage HI /IV.TNM staging of tumor was independent prognostic factor.

关 键 词：胃肿瘤 青年 临床病理特征 预后 

分 类 号：R735.2[医药卫生—肿瘤]