中西医结合治疗脑小血管病伴发非痴呆血管性认知功能损害的临床研究  

Clinical Study on the Treatment of Cerebral Small Vessel Disease with Vascular Cognitive Impairment-no Dementia by Integrated Traditional Chinese Medicine and Western Medicine

作　　者：杨涛[1] 杨瑞龙[1] 

机构地区：[1]甘肃省中医院脑病科,甘肃兰州730050

出　　处：《西部中医药》2015年第4期111-113,共3页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察补脑膏联合尼莫地平治疗脑小血管病(CSVD)伴发非痴呆血管性认知功能损害(VCI-ND)的临床疗效。方法:将80例符合诊断标准的患者随机分为对照组、治疗组各40例。2组均口服尼莫地平,观察组同时口服补脑膏,2组连续治疗12周,比较治疗前后蒙特利尔认知评估量表(Mo CA)评分。结果:Mo CA评分2组治疗后均明显升高(P<0.05),观察组升高更明显(P<0.05)。结论:补脑膏联合尼莫地平治疗CSVD伴发VCIND患者,其疗效优于单独应用尼莫地平治疗者。Objective： To observe therapeutic effect ofBuNaoGaoand nimodipine in the treatment of cerebral small vessel disease （CSVD） with vascular cognitive impairment-no dementia（VCI-ND）. Methods： Totally 80 patients who met the diagnostic standard were randomly divided into the control group and the treatment group with 40 cases in each. Nimodipines was orally given to the patients in both groups, andBuNaoGaowas used only in the treatment group for 12 weeks consecutively. The scores of Montreal Cognitive Assessment （MoCA） before and after treatment were compared. Results： Scores of MoCA increased obviously in both groups （P〈0.05）, the improvement of the treatment group was more obvious （P〈0.05）. Conclusion： The clinical efficacy ofBuNaoGaocombined with nimodipine in the treatment of CSVD with VCI-ND is superior to that of nimodipine alone.

关 键 词：脑小血管病 非痴呆血管性认知功能损害 补脑膏 尼莫地平 

分 类 号：R743[医药卫生—神经病学与精神病学]