川芎晒干过程中阿魏酸和阿魏酸松柏酯含量的变化  

Dynamic Changes of Ferulic Acid and Coniferyl Ferulate in Chuanxiong Rhizom a during the Sun-drying Process

作　　者：王涛[1] 林良斌[2] 张巧玲[2] 李乐[2] 刘世勇[1] 李亚波[1] 张利[2] 

机构地区：[1]四川农业大学生命科学学院,四川雅安625014 [2]四川农业大学理学院,四川雅安625014

出　　处：《植物科学学报》2015年第2期259-263,共5页Plant Science Journal

基　　金：国家星火计划项目(2014GA810004);四川省科技支撑计划项目(2015FZ0002;2015SZ0102)

摘　　要：为了解新鲜川芎采后干燥过程中阿魏酸和阿魏酸松柏酯含量的动态变化规律,采用高效液相色谱法测定了川芎晒干过程中总阿魏酸、游离阿魏酸和阿魏酸松柏酯的含量。结果显示,在整个晒干过程中(30 d),总阿魏酸、游离阿魏酸和阿魏酸松柏酯含量呈先升高后下降的变化趋势,晾晒第3 d时总阿魏酸含量最高(0.23%),因此在晾晒的第3 d利用快速干燥技术能较好地保留川芎药材中总阿魏酸含量,使其发挥更佳的药效。川芎药材中的阿魏酸松柏酯能水解产生阿魏酸,因此研究川芎干燥过程中的生理响应与含水量的关系对阿魏酸积累有重要意义。由于川芎在用药过程中是以总阿魏酸含量发挥药效的,所以以总阿魏酸含量作为川芎药材质量控制指标更加科学。To investigate the dynamic changes of ferulic acids （total ferulic acid and free ferulic acid） and coniferyl ferulate in fresh Chuanxiong Rhizoma during the sun-drying process, the contents of both were determined by high performance liquid chromatography. Results revealed that the contents of total ferulic acid, free ferulic acid and coniferyl ferulate showed an increasing trend at first and then a decreasing trend during the drying process （30 d）. The maximum total ferulic acid content （0.23%） was found on the third day after drying. To retain the contents of total ferulic acid, quick drying technology should be used on the third day after drying. The results also suggested that coniferyl ferulate might serve as a storage of free ferulic acid, and the relationship between of physiological response and water content of ferulic acid accumulation in Chuanxiong Rhizoma during the drying process has important significance. Coniferyl ferulate was hydrolyzed into ferulic acid and coniferyl alcohol during processing. Ferulic acid was found to be the efficacy component of Chuanxiong Rhizoma, so total ferulic acid content as an index of Chuanxiong Rhizoma quality is scientific and reasonable.

关 键 词：川芎 晒干 阿魏酸 阿魏酸松柏酯 

分 类 号：Q946.8[生物学—植物学]