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机构地区:[1]复旦大学附属眼耳鼻喉科医院耳鼻咽喉科,上海200031
出 处:《临床耳鼻咽喉头颈外科杂志》2015年第9期865-868,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery
摘 要:前哨淋巴结(sentinel lymph node,SLN)是指淋巴回流途径上位于首站的一个或一组淋巴结,是区域淋巴结中最容易被肿瘤侵犯的淋巴结,因此SLN反映了整个淋巴结群的肿瘤转移状态。如果SLN阴性,则其引流区域的其他淋巴结发生转移的可能性很小。所以可以根据SLN有无转移来协助判断区域淋巴结的状况,决定是否行淋巴结清扫术及清扫范围。增强CT扫描和MRI检查是目前临床上诊断淋巴结转移的主要方法,但无法判断正常大小的淋巴结是否发生转移。Summary Whether the sentinel lymph node (SLN) metastasis has important clinical significance for the therapy and prognosis of tumor. Sentinel lymph node biopsy (SLNB) has became the most accurate clinical method to confirm the status of sentinel lymph node. And the key of the success of SLNB is the localization of SLN. The methods used to locate SLN mainly are blue dye tracer method, radionuclide tracer technique, blue dye tracer method combined with radionuclide tracer technique, indirect lymphography, NIR imaging, and photoacoustic imaging. This article demonstrates the principle, application method and contrast agents of the indirect lymphography and the application in head and neck tumor.
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