磁共振扩散加权成像在肝癌化疗栓塞术后疗效评价中的应用  

The value of MR diffusion-weighted imaging in the assessment of tumor response after TACE in patients with hepatocellular carcinoma

作　　者：杨欢 李文涛 许立超[1,2] 

机构地区：[1]复旦大学附属肿瘤医院介入科 [2]复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国癌症杂志》2015年第4期311-315,共5页China Oncology

摘　　要：经导管肝动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)是临床不可切除肝癌的主要治疗方法,扩散加权成像(diffusion weighted imaging,DWI)作为一种无创的MRI功能成像,能先于肿瘤形态学改变,观察到肿瘤的功能改变,在肝癌化疗栓塞术后的随访中,能够及时、准确地检测到肝内新发病灶,鉴别肿瘤组织的坏死和残留。Transcatheter arterial chemoembolization （TACE） is the main treatment method for advanced hepatocellular carcinoma （HCC）. As a non-invasive functional MR imaging, diffusion weighted imaging （DWI） can reflect the functional changes in tumor before morphologic changes. In the follow-up of HCC after TACE, DWI can detect new lesions and distinguish necrotic neoplastic tissue and residual neoplastic tissue timely and accurately.

关 键 词：肝癌 扩散加权成像 经导管动脉化疗栓塞 表观弥散系数 随访 

分 类 号：R730.44[医药卫生—肿瘤] R735.7[医药卫生—临床医学]