CT引导下颅脑穿刺活检术23例  

The clinical application of CT-guided craniocerebral puncture biopsy: initial experience in 23 cases

作　　者：刘健[1] 刘瑞青[1] 曹会存[1] 王振豫[1] 曹广劭[1] 刘诗义[1] 李天晓[1] 

机构地区：[1]郑州大学河南省人民医院介入治疗中心肿瘤及综合病区,郑州450003

出　　处：《介入放射学杂志》2015年第5期438-441,共4页Journal of Interventional Radiology

摘　　要：目的探讨CT引导下颅脑占位穿刺活检术对神经系统疾病的诊断意义及安全性。方法 2013年4月至2014年6月行CT引导下行颅脑占位穿刺活检术共23例。所有患者均具有神经系统临床症状或体征,影像学检查提示颅内占位。CT引导下颅脑占位穿刺活检术行病理学或细菌学检查,对其结果进行分析。结果本组患者中明确病理诊断19例,活检阳性诊断率82.6%(19/23)。其中14例(60.9%)获得肿瘤学病理诊断,主要包括脑胶质瘤、非霍奇金淋巴瘤、胚胎发育不良性神经上皮肿瘤、脉络丛乳头状肿瘤、表皮样囊肿等;5例(21.7%)为非肿瘤性病变,包括脓肿、脑胶质细胞增生症、脑毛细血管扩张症等。活检穿刺术后少量血肿者1例(4.3%),本组病例穿刺活检术后无颅内感染、癫痫等并发症。结论 CT引导下脑穿刺活检术创伤小,并发症少,可以为颅脑病变提供明确病理学诊断,是一种具有较广阔应用前景的技术。Objective To investigate the diagnostic value of CT-guided craniocerebral puncture biopsy, and to discuss its clinical safety. Methods During the period from April 2013 to June 2014 at authors’ hospital CT-guided craniocerebral puncture biopsy was carried out in 23 patients. All patients had clinical symptoms or signs of nervous system. Imaging examination revealed that all patients had intracranial space-occupying lesions. CT-guided craniocerebral puncture biopsy was performed to make pathological or bacteriological examinations. The results were statistically analyzed. Results In this group of patients, definite pathological diagnosis was made in 19 cases, biopsy positive diagnosis rate of biopsy was 82.6% （19/23）, among them oncology-pathological diagnosis was obtained in 14 cases （60.9%）, mainly including glioma, non-Hodgkin lymphoma, dysembryoplastic neuroepithelial tumor, choroid plexus papillary tumor, epidermoid cyst, etc. Non-neoplastic lesion was confirmed in 5 cases （21.7%）, including suppurated meningitis, cerebral gliosis hyperplasia, cerebral telangiectasis, etc. Small amount of subdural hemorrhage was observed in one case （4.3%）. No severe complications, such as intracranial infection or epilepsy, occurred in all patients. Conclusion CT-guided craniocerebral puncture biopsy is minimally-invasive with fewer complications, it can provide definite diagnosis for intracranial lesions, therefore, this technique has a broad development prospect in clinical practice.

关 键 词：颅脑病变 穿刺活检 CT引导技术 

分 类 号：R741[医药卫生—神经病学与精神病学]