声触诊组织定量技术在乳腺结节鉴别诊断中的影响因素分析  

Analysis of the Infl uence Factors of VTQ in Differential Diagnosis of Breast Nodules

作　　者：谢倩倩[1] 宁春平[1] 禹静[1] 王建红[1] 房世保[1] 孙咏梅[1] 

机构地区：[1]青岛大学医学院附属医院超声科,山东青岛266000

出　　处：《中国医疗设备》2015年第5期54-57,共4页China Medical Devices

摘　　要：目的探讨声触诊组织定量技术(Virtual Touch Tissue Quantification,VTQ)在乳腺良恶性结节鉴别诊断中的影响因素。方法对经手术或活检病理检查证实的92例乳腺结节患者行常规超声及VTQ检查,记录结节的常规超声图像特征、大小、深度及剪切波速度(Shear Wave Velocity,SWV)。采用受试者工作特征曲线分析VTQ技术对良恶性乳腺结节的鉴别诊断价值。采用多元逐步回归方法评估SWV值的可能影响因素,并以最大径2.0 cm为界,评估不同亚组结节SWV值的影响因素。结果 VTQ技术鉴别良恶性乳腺结节的灵敏性为90.0%,特异性为92.0%,准确性为80.2%,曲线下面积为0.917。病理性质及内部血流分级对全部结节及最大径<2.0 cm结节亚组的SWV值有影响,结节最大径线对最大径≥2.0 cm亚组结节的SWV值有影响。结论 VTQ技术为超声评估乳腺占位性病变提供了一种新方法。Objective To discuss the influence factors of VTQ （Virtual Touch Tissue Quantification） in differential diagnosis of benign and malignant breast nodules. Methods Ninety-two breast nodules patients who had been confirmed through surgeries or pathological tissue biopsies were examined by conventional ultrasound and VTQ so as to record the features of conventional ultrasound images as well as the size, depth and SWV （Shear Wave Velocity） of the nodules. The ROC （Receiver Operating Characteristic） curve was adopted to perform differential diagnosis of benign and malignant breast nodules. Moreover, the methodology of multiple stepwise regressions was also deployed to assess the potential influence factors of SWV values. And the maximum diameter of 2.0 cm was taken as a standard to assess the influence factors of SWV values for sub-group nodules. Results The sensitivity, specificity and accuracy of VTQ in differential diagnosis of benign and malignant breast nodules were 90.0%, 92.0% and 80.2% respectively; and the AUC （Area under Curve） was 0.917. The pathological nature and internal blood flow grading had influences on SWV value in the whole cases and nodules 〈 2.0 cm; while the maximum diameter standard of nodules had influences on the SWV value in the cases with sub-group nodules ≥ 2.0 cm. Conclusions VTQ provided a new method for differential diagnosis of breast nodules using ultrasonography.

关 键 词：乳腺结节 弹性成像 声触诊组织定量技术 剪切波速度 超声诊断仪 

分 类 号：R737.9[医药卫生—肿瘤]