眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究  

Exploring laser and lucentis treatment of diabetic retinopathy

作　　者：张书林[1] 尧雪洲[2] 

机构地区：[1]云南省第二人民医院眼科,云南昆明650021 [2]云南中医学院基础医学院,云南昆明650500

出　　处：《中国医学装备》2015年第5期78-81,共4页China Medical Equipment

摘　　要：目的:探讨眼底激光联合雷珠单抗治疗糖尿病视网膜病变(DR)的临床效果。方法:选取102例DR患者,根据治疗方式的不同将其分为观察组(53例)和对照组(49例)。观察组患者采用眼底激光联合雷珠单抗治疗,对照组患者单纯应用眼底激光治疗。结果:观察组患者治疗后视力提高率为67.9%,视力下降率为13.2%,显著好于对照组,两组相比较其差异有统计学意义(x2=4.60,x2=3.87;P<0.05)。治疗后观察组眼底出血、渗出、视网膜水肿改善明显优于对照组,两组相比较其差异有统计学意义(t=4.17,t=3.92,t=4.06;P<0.05)。结论:针对DR患者采用眼底激光与雷珠单抗联合治疗可明显改善视网膜相关症状,对其视力恢复具有良好推动作用。Objective： To analysis the effects of laser and lucentis treatment of diabetic retinopathy. Methods：Fifty-three patients with DR were treated with laser and lucentis in our hospital from October 2012 to October 2013 as observer group. Forty-nine patients with DR were treated with laser in our hospital from September 2011 to September 2012 as control group. Results：The results indicated that visual acuity improved rate was 67.9%and decreased vision rate was 13.2% in observer group. Vision conditions in the observation group was better than that in the control group with significant difference （x2=4.60, x2=3.87; P〈0.05）. Simultaneously, improve time of hemorrhage, exudates, edema and macular thickness in the observation group was better than that in the control group with significant difference （t=4.17, t=3.92, t=4.06; P〈0.05）. Conclusion： The laser and lucentis treatment of diabetic retinopathy can significantly improving symptoms of retinal and promoting visual recovery.

关 键 词：糖尿病性视网膜病变 眼底激光 雷珠单抗 临床疗效 

分 类 号：R774.1[医药卫生—眼科]