肝性脑病治疗的新进展  

New progress in the treatment of hepatic encephalopathy

作　　者：阎明[1] 崔瑞冰[1] 

机构地区：[1]山东大学齐鲁医院老年消化病科,济南250002

出　　处：《中华消化病与影像杂志（电子版）》2015年第2期1-3,共3页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

摘　　要：肝性脑病是各种严重肝脏疾病所致的以代谢紊乱为基础的中枢神经系统功能失调综合征,以精神神经症状为主,临床表现为性格智力改变、行为失常、意识障碍和昏迷等。肝性脑病的病因及发病机制复杂,但关注最多的仍是氨中毒学说,故现在肝性脑病的治疗主要集中于减少氨的产生和吸收,但随着新的发病机制的明确,许多新的治疗方法可用于临床治疗。Hepatic encephalopathy （ HE ） is a complex neuropsychiatric syndrome caused by a metabolic disorder, which may complicate acute, chronic liver failure or patients with portal-systemic shunting.It is characterized by changes in mental state including a wide range of neuropsychiatric symptoms ranging from personality changes,behavior disorder,a depressed level of consciousness and coma.The etiology and pathogenesis of HE are complicated,but ammonia is believed to play crucial role in pathogenesis of HE. At present,treatment of HE aims at decreasing the production and intestinal absorption of ammonia.But as the role of new pathogenetic mechanisms becomes clear,many potential new treatment strategies may become available for clinician.

关 键 词：肝性脑病 治疗 进展 

分 类 号：R575.3[医药卫生—消化系统]