中老年心脑血管疾病患者骨密度测定的临床意义  

Clinical Significance of Bone Mineral Density Detection in Middle-aged and Elderly Patients with Cardiocerebrovascular Diseases

作　　者：黄洁明[1] 钟冕[1] 

机构地区：[1]广东省佛山市第一人民医院,广东佛山528000

出　　处：《医学临床研究》2015年第4期678-680,共3页Journal of Clinical Research

摘　　要：【目的】探讨骨密度测定在中老年心脑血管疾病患者中的临床意义，进一步了解骨质疏松与心血管疾病的关系。【方法】对本院347例中老年心脑血管病患者行骨密度检测，并按检测结果分为三组（骨量正常组，骨量减少组，骨质疏松组），记录收缩压（SBP）、舒张压（DBP）、总胆固醇（TC）、三酯甘油（TG）、低密度脂蛋白胆固醇（LDL‐C ）、高密度脂蛋白胆固醇（HDL‐C ）等指标。【结果】高血压病、冠心病、脑血管病各疾病中骨质疏松，骨量减少者发生率明显高于骨量正常者，且差异均有显著性（χ^2值分别为8．46，5．02，4．37，均 P＜0．05）。各组女性骨质疏松发生率发生率高于男性，且差异均有显著性（χ^2值分别为14．62，8．97，6．44，均 P＜0．05）。骨质疏松组血压、TC、HDL‐C较骨量正常组明显升高，且差异有显著性（ P ＜0．05或 P ＜0．01）。【结论】骨密度是中老年心脑血管疾病患者需要监测的指标，骨质疏松与心脑血管疾病危险因素有内在关系，其有着相同的病理生理机制。[Objective] To explore the clinical significance of bone mineral density （BMD ） detection in middle‐aged and elderly patients with cardiocerebrovascular diseases for further elucidating the relationship be‐tween osteoporosis and cardiocerebrovascular diseases .[Methods] BMD was measured by dual‐energy X‐ray absorptiometry .A total of 347 patients with cardiocerebrovascular diseases were divided into three groups of normal BMD ,low BMD and osteoporosis .And analyses were performed for the parameters of systolic blood pressure （SBP） ,diastolic blood pressure （DBP） ,total cholesterol （TC） ,serum triglyceride （TG） ,low densi‐ty lipoprotein （LDL‐C） and high density lipoprotein （HDL‐C） .[Results] The value of BMD was low among kinds of cardiocerebrovascular diseases ,the morbidity of osteoporosis was high .Significant differences existed in blood pressure , TC and HDL‐C among three BMD groups （ P 〈 0 .01 ） .[Conclusion] BMD detection should be monitored for cardiocerebrovascular diseases .Close correlations exist between osteoporosis and car‐diovascular risk factors .And there are some common pathophysiologic mechanisms .

关 键 词：心血管疾病 骨密度 骨质疏松 危险因素 

分 类 号：R743[医药卫生—神经病学与精神病学]