脑出血并应激性溃疡患者血浆和肽素的变化及意义  

Change of the level of copeptin in plasma and its sigificance in patients with intracerebral hemorrhage combined with stress ulcer

作　　者：孙川川[1] 杜业亮[2] 周俊妍[1] 仇学亮 祝艳芳[1] 

机构地区：[1]潍坊医学院研究生院,山东潍坊261042 [2]山东省潍坊市人民医院脑科医院神经内科,261021

出　　处：《中国医师进修杂志》2015年第5期330-332,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的 探讨脑出血并应激性溃疡患者血浆和肽素水平的变化及意义.方法 收集脑出血患者80例,其中单纯脑出血49例,脑出血并应激性溃疡31例;选择健康体检者30例作为对照.入选者均检测血浆和肽素水平,并进行比较.结果 单纯脑出血患者和脑出血并应激性溃疡患者血浆和肽素水平明显高于对照者[（303.684±68.691）和（527.034±74.111） ng/L比（121.460±53.364） ng/L],而且脑出血并应激性溃疡患者明显高于单纯脑出血患者,差异有统计学意义（P＜0.05）.结论 脑出血患者血浆和肽素水平明显升高,而且脑出血并应激性溃疡患者更高.Objective To explore the change of copeptin in plasma and its significance in patients with intracerebral hemorrhage combined with stress ulcer.Methods Eighty patients with intracerebral hemorrhage were collected.Forty-nine patients of pure intracerebral hemorrhage and 31 patients of intracerebral hemorrhage combined with stress ulcer were included.Thirty healthy people were taken as controls.The level of copeptin in plasma was measured and compared in all subjects.Results The level of copeptin in plasma in patients with pure intracerebral hemorrhage and intracerebral hemorrhage combined with stress ulcer was significantly higher than that in controls：（303.684 ± 68.691）,（527.034 ± 74.111） ng/L vs.（121.460 ± 53.364） ng/L,and the level of copeptin in plasma in patients with intracerebral hemorrhage combined with stress ulcer was significantly higher than that in patients with pure intracerebral hemorrhage.The differences were statistically significant （P 〈 0.05）.Conclusion The level of copeptin in plasma in patients with pure intracerebral hemorrhage increases significantly,and it is much higher in patients with intracerebral hemorrhage combined with stress ulcer.

关 键 词：脑出血 应激性溃疡 和肽素 

分 类 号：R743.34[医药卫生—神经病学与精神病学]