重复超声内镜穿刺在胰腺囊实性病变诊断中的价值  

Diagnostic value of repeated EUS-FNA for pancreatic solid-cystic lesions

作　　者：孟茜茜[1] 朱建伟[1] 辛磊[1] 林寒[1] 侯晓佳[1] 田波[1] 王洛伟[1] 

机构地区：[1]第二军医大学附属长海医院消化内科,上海200433

出　　处：《中国临床医生杂志》2015年第5期21-23,共3页Chinese Journal For Clinicians

基　　金：上海市自然科学基金"中国人胰腺癌全基因组甲基化分析探讨早期诊治分子标记物"(12ZR1438800)

摘　　要：目的对临床怀疑胰腺癌而首次超声内镜下细针穿刺(EUS-FNA)诊断不明确的患者,重复行EUS-FNA细胞学检查和18F-氟脱氧葡萄糖(18F-FDG)正电子发射断层显像(PET)-CT扫描检查对胰腺癌诊断的对比研究。方法收集首次EUS-FNA结果不明确重复EUS-FNA和PET-CT的患者,进行配比分析。结果重复EUS-FNA的准确率为80%,敏感性为72.7%,特异性为100%,阳性预测值为100%,阴性预测值为57.1%;PET-CT检查的准确率为75%,敏感性为66.7%,特异性为83.3%,阳性预测值为80%,阴性预测值为71.4%。结论临床怀疑胰腺癌而首次EUS-FNA结果不明确时,重复EUS-FNA和PET-CT都是可行的方法,重复EUS-FNA略优于PET-CT检查。Objective To comparatively evaluate the diagnostic value of repeated Endoscopic Ultrasound-guided Fine-needle Aspiration （EUS-FNA） and 18F-FDG PET-CT among patients with suspicion for pancreatic cancer. Method Patients with suspected pancreatic cancer after unclear results of the first EUS-FNA cytology were recruited from our hospital, Second Military Medical University during Jan. 2008 and Oct. 2014. The information of repeated EUS-FNA and PET-CT imaging were collected respectively ratio analysis. Result The accuracy, sensitivity, specificity, positive predictive value and negative predictive value were 80%, 72. 7%, 100%, 100% and 57. 1% for repeated EUS-FNA, and 75%, 66. 7%, 83. 3%, 80% and 71. 4% for PET-CT respectively. Conclusion For the patients of suspected pancreatic cancer who first performed EUS-FNA cytology with unclear results, repeated EUS-FNA is slightly better than PET-CT as a further examination for diagnosis.

关 键 词：胰腺癌 超声内镜下细针穿刺 脱氧葡萄糖 

分 类 号：R735.9[医药卫生—肿瘤]