奥拉西坦联用B族维生素治疗血管性痴呆的疗效分析  

Clinical effects of oxiracetam B-vitamins on vascular dementia

作　　者：邵枝定[1] 张洁[1] 顾长斌[1] 

机构地区：[1]皖南医学院第二附属医院老年病科,安徽芜湖241000

出　　处：《皖南医学院学报》2015年第3期249-251,共3页Journal of Wannan Medical College

摘　　要：目的:分析奥拉西坦联用不同药物治疗血管性痴呆的疗效差异。方法:63例血管性痴呆患者分为两组:单用奥拉西坦组、奥拉西坦联用维生素B12、维生素B6和叶酸组。对患者用药前后的MMSE评分和ADL评分进行比较,分析两组疗效差异。结果:两种治疗方式均可提高患者MMSE评分和ADL评分;奥拉西坦联用维生素B12、B6及叶酸组效果优于单用奥拉西坦组。结论:奥拉西坦联用族维生素B12、B6及叶酸能更好改善血管性痴呆的认知水平。Objective： To observe the clinical effects of combined oxiracetam with B-vitamins and folic acid on vascular dementia. Methods： Sixty-three patients with vascular dementia were divided into two groups. Group I received oxiracetam,and GroupⅡ were given oxiracetam plus vitamin B12,B6 and folic acid. The two groups of patients were evaluated with Mini-Mental State Exam（ MMSE） and Activities of Daily Living（ ADL） before and after medication,and examined concerning the therapeutic effects. Results： Although two regimens had boosted the scores on MMSE and ADL,yet oxiracetam plus vitamin B12,B6 and folic acid had produced better results. Conclusion： Oxiracetam plus vitamin B12,B6 and folic acid may effective improve the recognition of patients with vascular dementia.

关 键 词：血管性痴呆 同型半胱氨酸 奥拉西坦 B族维生素 

分 类 号：R749.13[医药卫生—神经病学与精神病学]