硫杂杯芳烃冠醚的合成及其与氨基酸配合性能的研究  

Study on synthesis and amino acid coordination properties of thiacalixcrowns derivatives

作　　者：尚冀宁[1] 赵夏[1] 杨发福[2] 

机构地区：[1]银川能源学院石油化工系,宁夏银川750105 [2]福建师范大学化学与材料学院,福建福州350007

出　　处：《化学研究与应用》2015年第5期693-695,共3页Chemical Research and Application

基　　金：国家自然科学基金项目(20402002)资助;福建省自然科学基金项目(E0220002;2009J019)资助;银川能源学院科学研究项目(2013-KY-Z-05)资助

摘　　要：在普通杯芳烃骨架中引入硫原子可以改善普通杯芳烃的配合性能。文中首先合成了硫杂杯[4]芳烃四酰肼衍生物3,在弱酸的催化下继续与化合物4反应,高产率地合成了同时含酰胺和席夫碱单元的硫杂杯[4]芳烃冠醚衍生物5,新化合物的结构经1H NMR、元素分析、ESI-MS等表征证实。同时探讨了新型硫杂杯[4]芳烃衍生物5与系列-α氨基酸的配合性能。Introduction of sulfur atom could improve the matching performance of calixarenes. Firsthy,the hiacalix[4] arene hydra-zides derivative 3 was synthesized. By treating thiacalix[4] arene hydrazides derivative 3 with aryl aldehyde derivatives 4 in weak acid catalyst,the novel thiacalix[4] crowns derivatives 5 containing amides and schiff-base units were synthesized in high yields. The structure of the new compounds were confirmed by elemental analyses,ESI-MS,1 H NMR spectra. At the same time the compl-exation properties of novel thiacalix[4]arene derivatives 5 and series of alpha amino acids were explored.

关 键 词：硫杂杯4芳烃 冠醚 合成 氨基酸 

分 类 号：O623[理学—有机化学]