典必殊眼膏联合睑板腺按摩治疗睑缘炎临床观察  

To observe the clinical effect of Tovramycin and Drxamethasone Eye Ointment unite meibomian gland message for chronic blepharitis treatment

作　　者：陈丹娜[1] 吴建妹[1] 许丽疆[1] 

机构地区：[1]莆田学院附属医院眼科,福建莆田351100

出　　处：《泰山医学院学报》2015年第2期153-155,共3页Journal of Taishan Medical College

摘　　要：目的慢性睑缘炎在红霉素眼膏和思然眼水的治疗基础上加用典必殊眼膏联合睑板腺按摩后的疗效观察。方法慢性睑缘炎患眼120眼,裂隙灯下观察睑缘炎类型,其中前睑缘炎40眼,后睑缘炎40眼,混合型睑缘炎40眼,各类型随机分为A、B治疗组,A组常规给予红霉素眼膏局部涂眼,思然眼水点眼。B组在红霉素眼膏局部涂眼及思然眼水点眼基础上加用典必殊眼膏点眼联合睑板腺按摩,裂隙灯下观察睑板腺分泌物性状,角膜病变临床表现及病变范围,随访观察1年,比较两组治疗后复发率。结果治疗组总有效率为76.67%,对照组总有效率为46.16%,二者相比具有统计学差异(P〈0.05);治疗前睑缘炎相关角膜病各组间差异无统计学意义(P>0.05),治疗后1个月各组间区组统计P〈0.05〉;随访1年后,根据诊断标准,各组间复发比较P〈0.05,B组复发率小于A组。结论典必殊眼膏联合睑板腺按摩在睑缘炎治疗中具有良好的作用,可以有效地改善患者的症状和体征及治疗后复发。Objective：To observe the clinical effect of Tovramycin and Drxamethasone Eye Ointment unite meibomian gland message for chronic blepharitis treatment on the basic of using erythromycin eye ointment and Polyethylene Glycol Eye Drops. Methods：120 blepharitis eyes were divided into three groups：before blepharitis（1）,after blepharitis（2）and hybrid blepharitis（3）. Each type was randomly divided into A、B group,while group A used erythromycin eye ointment and Poly-ethylene Glycol Eye Drops,and group B used Tovramycin and Drxamethasone Eye Ointment unite meibomian gland message on the basic of the treatment of group A. Observe meibomian gland secretions ,clinical manifestations and scop of corneal le-sions under slit lamp. Were followed for 1 year,and compared the recurrence rate after treat. Result：The total effective rate of group B is 76. 67% ,and group A is 46. 16% ,both are statistically significant（P 0. 05）. After 1 month treat-ment,there was statistically significant difference between the groups（P 〈 0. 05）. After follow - up of 1 year,according to the diagnostic criteria ,there was statistically significant difference between the groups of recurrence（P 〈 0. 05）. Group B recurrence rates less than group A. Conclusion：Tovramycin and Drxamethasone Eye Ointment unite meibomian gland mes-sage have beneficial effect on blepharitis treatment,effectively improve sympotoms and signs,and reduce the recurrence rate.

关 键 词：睑缘炎 典必殊眼膏 睑板腺按摩 

分 类 号：R777.1[医药卫生—眼科]