直径大于3厘米的周围型肺癌血流动力学的多排螺旋CT动态增强扫描研究  

Dynamic Enhanced Spiral CT Scan on the Hemodynamics of Diameter 3 cm above the Peripheral Lung Cancer

作　　者：周春容[1] 胡帮聪 曹跃勇[1] 郑婷[2] 曾宪辉[1] 崔长乐[3] 

机构地区：[1]宜宾市第二人民医院放射科,四川宜宾644000 [2]泸州医学院附属医院放射科,四川泸州646000 [3]同济大学,上海200001

出　　处：《现代生物医学进展》2015年第18期3517-3519,3516,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金面上项目(81071213)

摘　　要：目的:研究直径3厘米以上周围型肺癌血流动力学的螺旋CT(电子计算机断层扫描,Computed Tomography)动态增强扫描的特点。方法:选取我院收治的肿瘤直径>3 cm的周围型肺癌患者55例,肺部腺瘤(良性)患者10例,肺部炎性结节患者26例。分别进行螺旋CT动态增强扫描,记录其CT值、强化峰值(Peak enhancement,PH),绘制动态增强时间-密度曲线,计算并比较曲线最大增强线性斜率(steepes slope,SS)以及血流灌注量(blood perfusion,BP)。结果:肺部炎性结节患者的密度曲线在120 s达到最大值;肺癌患者的密度曲线至65 s达到高峰;胸腺瘤患者的密度曲线变化不明显。肺癌组PH平均值大于胸腺瘤组,差异有统计学意义(P<0.05);胸腺瘤组PH平均值小于肺部炎性结节组,差异有统计学意义(P<0.05);肺癌组SS和BP大于胸腺瘤组,差异有统计学意义(P<0.05);胸腺瘤组SS和BP小于肺部炎性结节组,差异有统计学意义(P<0.05)。结论:螺旋CT动态增强扫描能够反映直径3厘米以上周围型肺癌的血流动力学特点从而有助于在肺癌的诊断和鉴别诊断。Objective： To study the hemodynamic characteristics of dynamic scanning of a diameter of 3 cm or more peripheral lung cancer enhanced spiral CT. Methods： 55 cases of patients with peripheral lung cancer, thymoma（benign） of 10 patients, 26 cases of pulmonary inflammatory nodule in our hospital were selected. Under the dynamic enhanced spiral CT scan, recording its CT value, peak enhancement（PH）, rendering dynamic time density curve, maximum enhancement steepes slope（SS） and blood perfusion（BP）. Results：The density curve of patients in pulmonary inflammatory nodules group reached the maximum at 120 s, in lung cancer reached the maximum at 65 s, and in undulating thymoma group there was no change. The average value of PH in lung cancer group was significantly higher than that of the thymoma group（P〈0.05）; the average PH in thymoma group was significantly lower than that of the pulmonary inflammatory nodule group（P〈0.05）. Lung cancer group SS and BP is greater than the thymoma, the difference was statistically significant（P〈0.05）; Thymoma group SS and BP is less than pulmonary inflammatory nodule group, the difference was statistically significant（P〈0.05）. Conclusion： Dynamic enhanced spiral CT scan can reflect more than 3 cm in diameter of peripheral lung cancer hemodynamic characteristics so as to help in the diagnosis and differential diagnosis of lung cancer.

关 键 词：周围型肺癌 血流动力学 螺旋CT 增强 

分 类 号：R734.2[医药卫生—肿瘤]