比较后腹腔镜下节段性与全肾动脉阻断肾部分切除术对术后患侧肾功能的影响  被引量:3

The study comparing of laparoscopic segmental and non segmental renal artery block partial nephrectomy may affect postoperative side kidney function

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作  者:杨昊[1] 陈方敏[2] 石家齐[2] 李登宝[2] 陈程[2] 

机构地区:[1]贵阳医学院,贵阳550004 [2]贵阳医学院附属医院泌尿外科

出  处:《临床泌尿外科杂志》2015年第5期393-396,共4页Journal of Clinical Urology

基  金:贵州省科技厅国际合作项目〔编号黔科合外G字(2011)7015;黔科合J字(2013)GZ62172〕

摘  要:目的:对比后腹腔镜节段性肾动脉阻断(SRPN)与普通全肾动脉阻断保留肾单位。肾部分切除术(LPN)对术后患侧肾功能的影响。方法:回顾性分析我院2010年6月~2012年6月治疗的80例局限性肾肿瘤(SRM)患者的临床资料,其中35例患者行SRPN,另45例患者行LPN。术前行肾动态显像及GFR检查,测得患侧GFR值;术后通过电话随访,每3~6个月复查肾动态显像及GFR,监测术后患侧GFR的变化,并进行统计学分析。结果:术后3、6个月,35例行SRPN患者术后患侧GFR和术前患侧GFR分别发现2例(2/35,5.71%)、3例(3/35,8.57%)下降,下降均值分别为(O.36±0.22)、(3.96±1.45)ml/min;而45例LPN患者术后患侧GFR和术前患侧GFR分别发现25例(25/45,55.56%)、30例(30/45,66.67%)下降;下降均值分别为(6.28±0.82)、(11.47±3.22)ml/min(P〈0.05)。术后随访12、18、24个月,SRPN患侧GFR与术前比较,下降分别为31.4%(11/35)、42.8%(15/35)、45.7%(16/35),下降均值分别为(8.52±2.16)、(11.02±2.23)、(13.55±2.68)ml/rain;LPN分别为86.67%(39/45)、88.89%(40/45)、93.33%(42/45),下降均值分别为(12.68±3.84)、(17.73±4.82)、(20.24±4.96)ml/min(P〈0.05).。结论:SRPN在术后早期(3~6个月)能最大限度地保护患肾功能,在保护肾功能方面具有明显优势;但远期(12~24个月)随访,两种术式患侧GFR均有不同程度的下降,提示SRPN在远期保护肾功能有个体化特点;通过两种术式术后患侧GFR的比较,说明sRPN是治疗SRM的一种安全有效的手术方法,值得临床推广应用。Objective: Comparing of laparoscopic nephron-reserved partial nephrectomy with the segmental re- nal artery hlocking(SRPN) with common laparoscopic partial nephrectomy(LPN) in effect on postoperative affect- ed side kidney function. Method: Retrospectively collecting of 80 cases of patients with renal localised tumor from June 2010 to June 2012, 35 cases recieved SRPN, another 45 patients recieved LPN. Preoperative renal dynamic imaging and GFR, with bilateral GFR values were measured. All postoperative data were followed up by telephone per 3-6 months, which included reviewing of GFR and renal dynamic imaging, monitoring postoperative changes of bilateral GFR, and were statistical analysed. Result: After operative 3,6 months, affected side postoperative GFR compaTing with preoperative GFR in SRPN were found falling in 2 of 35 cases (5.71%), 3 of 35(8.57%) respec- tively, and the declining GFR value were average (0.36 ±0.22), (3.96±1.45) ml/min respectively( P 〉0.05). However, that of LPN 45 cases were found in 35 of 45 cases (77.8%), 42 of 45 cases(84.4%) falling respective- ly, the declining average GFR value with (6.28±0.82), (11.47±3.22) ml/min respectively ( P 〈 0.05), the rate and value of falling of affected side postoperative GFR in SRPN group vs LPN group were diferrence signifi- cantly (P〈 0.05). Follwing up in postoperative 12, 18, 24 months, affected side GFR value were compared with preoperative in SRPN, GFR declining in 31.4%(11/35), 42.8%(15/35), 45.7%(16/35) respectively, fall- ing average GRF value with (8.52±2.16), (ll. 02±2.23), (13.55±2.68) ml/min respectively. In LPN, posto-perative affected side GFR declining 86.67% (39745), 88.89% (40/45), 93.33% (42/45) respectively, average GFR value falling with (12.68±3.84), (17.73±4.82), (20.24±4.96) ml/min respectively. Data in SRPN vs LPN were diferrence significantly( P 〈 0.05). Conclusion: In early postoperative (3-6 m

关 键 词:肾肿瘤 腹腔镜肾部分切除术 节段性肾动脉阻断 全肾动脉阻断 

分 类 号:R737.11[医药卫生—肿瘤]

 

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