计算机辅助诊断定量分析表现为磨玻璃样结节的肺原位腺癌与非典型腺瘤样增生  

Computer-aided Differential Diagnosis of Adenocarcinoma Insitu and Atypical Adenomatous Hyperplasis Which Appear as Ground Glass Opacity

作　　者：矫娜[1] 吴明祥[1] 龚静山[1] 马捷[1] 孙黎明[1] 

机构地区：[1]暨南大学第二临床医学院(深圳市人民医院)放射科,广东深圳518000

出　　处：《中国CT和MRI杂志》2015年第6期29-31,共3页Chinese Journal of CT and MRI

基　　金：深圳市卫生计生系统科研项目(NO:201401008)

摘　　要：目的探讨计算机辅助诊断(CAD)定量分析对原位腺癌(AIS)与非典型腺瘤样增生(AAH)的鉴别诊断价值。方法采用自编软件对125例经CT发现的磨玻璃样结节进行组织特征分析,比较AIS和AAH在CT直方图上的差异。结果 AIS组的病灶平均直径大于AAH组的,但两者差距无统计学意义(P>0.05);AAH组的CT值与CT峰值均明显小于AIS组,差异具有显著性意义(P<0.001);且CT峰值<-620,则AAH的可能性更大。直方图中,若出现双峰或多峰,可以除外AAH。结论基于计算机辅助诊断技术的组织成分分析能很好的鉴别表现为磨玻璃样结节的AAH与AIS。Objective To study the clinical application value of computer-aided diagonosis in differentiating atypical adenomatous hyperplasia from adenocarcinoma insitu.Methods 125 cases of ground glass opacity detected by CT were diagonosized by self-designed soft, to compare the difference between AIS and AAH.Results There was no significant difference in lesion size between AIS and AAH （P〉0.05）. The peak and mean CT value of AAH were obviously lower than that of AIS,with significant difference （P〈0.001）. If the peak of CT value〈-620,it was more likely to be AAH. In the CT histogram, double-peak or multi-peak can except for the possibility of AAH.Conclusion Tissue components analysis basede on computer-aided diagonosis can perfectly identify AAH and AIS which appear as ground glass nodules.

关 键 词：计算机辅助诊断 磨玻璃样结节 肺肿瘤 

分 类 号：R322.35[医药卫生—人体解剖和组织胚胎学]