鼻胆管引流预防内镜逆行胰胆管造影术后胰腺炎及高淀粉酶血症疗效的Meta分析  

Efficacy of endoscopic nasobiliary drainage for prevention of post-ERCP pancreatitis and hyperamylasemia: a Meta analysis

作　　者：刘苗[1] 邓涛[1] 杨艳[1] 林萍[1] 汪维波[1] 

机构地区：[1]武汉大学人民医院消化内科,湖北武汉430060

出　　处：《胃肠病学和肝病学杂志》2015年第5期531-534,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的系统评价鼻胆管引流（endoscopic nasobiliary drainage,ENBD）能否有效、安全地预防内镜逆行胰胆管造影术（endoscopic retrograde cholangiopancreatography,ERCP）后胰腺炎（post-ERCP pancreatitis,PEP）及高淀粉酶血症。方法通过计算机和人工检索文献资料（不限语种）,应用Jadad评分量表进行评分,利用Cochrane协作网提供的Rev Man 5.2软件进行统计学分析。结果纳入16篇文献,共2 674例患者,Meta分析结果显示：ENBD组PEP及高淀粉酶血症发病率低于对照组（RR=0.37,95%CI：0.31~0.45,P〈0.01）。结论 ENBD能够有效预防PEP及高淀粉酶血症。Objective To analyze the efficacy of endoscopic nasobiliary drainage （ENBD） in the prevention of post- endoscopic retrograde cholangiopancreatography （ERCP） pancreatitis and hyperamylasemia. Methods Informations were collected from computer and hardcopy （languages were not limited）. Jadad rating scale was used for scores （infor- mations were collected by two people independently）, data were analyzed by Cochrane Collaboration RevMan 5.2 soft- ware. Results Sixteen studies were identified and had 2 674 patients in all. The group of ENBD had a low morbity of post-ERCP pancreatitis and hyperamylasemia （RR =0.37, 95% CI： 0. 31 -0.45, P 〈0.01 ）. Conclusion ENBD can reduce the incidence of post-ERCP pancreatitis and hyperamylasemia.

关 键 词：鼻胆管引流 内镜逆行胰胆管造影术 术后胰腺炎 高淀粉酶血症 META分析 

分 类 号：R576[医药卫生—消化系统]