超选择性栓塞联合显微手术治疗后颅窝实质性血管母细胞瘤  

Applicattion of preoperative superselective endovascular embolization to microsurgery for substantial posterior fossa hemangioblastomas

作　　者：吕忠中 徐韬[1] 杨天明[1] 

机构地区：[1]南京明基医院神经外(南京医科大学附属明基医院神经外科),210000

出　　处：《中国临床神经外科杂志》2015年第5期274-276,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的探讨超选择性栓塞联合显微手术治疗后颅窝实质性血管母细胞瘤的临床效果。方法回顾性分析5例后颅窝实质性血管母细胞瘤患者的临床资料。所有患者均通过栓塞供血动脉后立刻行病灶显微切除术。结果 5例病人肿瘤均全切除,切除术中出血量为(200±80)ml。术后无明显神经功能障碍。术后3个月随访全部病人改良Rankin量表评分均0分,未见肿瘤复发。结论超选择性栓塞肿瘤供血动脉后立即行病灶显微切除术治疗后颅窝实质性血管母细胞瘤可减少术中出血,缩短手术时间,降低手术并发症及死亡率。Objective To investigate the clinical value of preoperative supperselective endovascular embolization to microsurgery for the substantial posterior fossa hemangioblastomas. Method The clinical data of 5 patients [male, 3 and female, 2; mean age, （41.2±11.3） years] with the substantial posterior fossa hemangioblastomas who underwent microsurgery immediately after the supperselective endovascular embolization were analyzed retrospectively, including the image data and therapeutic method and effects. Results The total excision of the hemangioblastomas was achieved in all the patients. The intraoperative bleeding volume was （200～80）ml. All the patients were perfectly recovered without any disorder of neurological function. The following up 3 months after the microsurgery showed that all patients had good outcomes （Modified Rankin scale scroe, 0） and the hemangioblastomas did not recurred in the patients. Conclusions The intraoperative bleeding volume and the operative complications may be reduced and operative duration may be shortened by the preoprerative supperselective endovasculative embolization in the patients with substantial posterior fossa hemangioblastomas.

关 键 词：血管母细胞瘤 显微手术 血管内栓塞 疗效 

分 类 号：R739.41[医药卫生—肿瘤] R651.11[医药卫生—临床医学]