三维适形放疗治疗复发性卵巢癌患者的临床疗效  

Clinical value of three dimensional conformal radiotherapy in the treatment of recurrent ovarian cancer patients

作　　者：毕利萍[1] 李玉军[1] 于晓彬[1] 张洪岩[1] 

机构地区：[1]中国石油天然气集团公司中心医院肿瘤科,廊坊065000

出　　处：《中国肿瘤临床与康复》2015年第6期699-701,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨三维适形放疗治疗复发性卵巢癌患者的临床疗效。方法选取68例复发性卵巢癌患者,其中单纯化疗的31例患者为对照组,化疗联合三维适形放疗治疗的37例患者为观察组。观察两组病患治疗后的改善效果、生存时间以及毒性反应情况,并行统计学处理分析。结果观察组病例中总缓解率为40.5%,总获益率为64.8%,平均无进展生存时间为(6.5±0.9)个月,平均总生存期为(12.3±1.9)个月,与对照组相比差异均有统计学意义(P<0.05)。结论复发性卵巢癌患者应用三维适形放疗可显著提高临床疗效,延长生存时间,并不伴随显著的不良反应,值得广泛应用。Objective To evaluate the clinical value of three-dimensional conformal radiotherapy in the treatment of recurrent ovarian cancer patients. Methods Totally 68 cases of patients with recurrent o- varian cancer were selected, in which 31 cases who were given chemotherapy treatment were set as the con- trol group, and another 37 cases of patients who were given three-dimensional conformal radiotherapy were set as the observation group. The effect of improving treatment, survival time, and toxic reactions of these two groups were observed and analyzed. Results In observation group, the overall response rate was 40. 5% , the total benefit rate was 64. 8% , the average progression-free survival time was （ 6. 5 ± 0. 9 ） months, the average overall survival was （12. 3 ± 1.9） months, the difference had statistically significant compared with control group （ P 〈 0. 05 ）. Conclusions For patients with recurrent ovarian cancer, three- dimensional conformal radiotherapy can significantly improve clinical effect, prolong survival time, is not ac- companied by significant side effects, andit is worthy widely used.

关 键 词：复发性卵巢肿瘤 三维适形放疗 临床疗效 不良反应 

分 类 号：R737.31[医药卫生—肿瘤]