血浆促动脉硬化指数(AIP)与缺血性脑血管病的相关性研究  

Plasma To promote atherosclerosis index(AIP) and the correlation of ischemic cerebrovascular disease research

作　　者：郑建文 董鸿智 赵锋仓 徐世林 莫芳萍 

机构地区：[1]西藏民族学院附属医院神经内科,陕西咸阳712082 [2]西藏民族学院附属医院检验科,陕西咸阳712082

出　　处：《中风与神经疾病杂志》2015年第5期446-448,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探讨血浆促动脉硬化指数(AIP)与缺血性脑血管病发生的关系。方法选择确诊为缺血性脑血管病患者286例作为观察组,选择同期健康体检者286例作为对照组,检测两组的血浆脂质代谢水平,包括总胆固醇(TC)、低密度脂蛋白(LDL-C)、甘油三酯(TG)及高密度脂蛋白(HDL-C),计算出血浆促动脉硬化指数(AIP),并进行对比分析。结果与健康对照组相比,缺血性脑血管病组患者TC、TG、LDL-C升高,而HDL-C下降,差异有统计学意义(P<0.01及P<0.05);而AIP值显著增高,差异有明显统计学意义(P<0.001)。结论 AIP与缺血性脑血管病的发生密切相关,AIP可以作为常规血脂分析中的一项较好的参数,其优于单项血脂测定分析,能够更全面地评估缺血性脑血管病发生的风险。Objective To investigate the correlation of plasma to promote atherosclerosis index （AIP） and ischemic cerebrovascular disease. Methods Selecting patients diagnosis diagnosed of isehemic eerebrovascular disease, 286 cases as observation group, choose the same physical examination,286 cases as control group, the deteetiondetecting of two groups of metabolism of plasma lipid levels, including total cholesterol （ TG）, low density lipoprotein （ LDL-C ）, triglycerides （TG） and high -density lipoprotein （HDL-C） of two groups, calculatinge the plasma to promote atherosclerosis index （AIP）, and doing comparison analysis. Results Compared with healthy controls ,TC, TG, LDL-C in patients group with ischemic cere- brovaseular disease group TC, TG, LDL-C riserose, while HDL-C fell, the difference was statistically significant （ P 〈 0.05 ） ; And AIP value increased significantly,and hasthe obvious differences have had statistical significance（ P 〈 0. 001 ）. Con- clusion AIP is closely related to the occurrence of ischemic ccrebrovascular disease, AIP can serve as a good parameter in normal blood lipid analysis, it iss better than the single lipid measurement analysis, can more fully assess the risk of ische- mic cerebrovascular disease.

关 键 词：缺血性脑血管病 血浆致动脉硬化指数 血脂 

分 类 号：R743[医药卫生—神经病学与精神病学]