甘松挥发性成分的气相色谱—质谱分析  

Analysis on volatile component of nardostachys root by using gas chromatography-mass spectroscopy

作　　者：吴杨 周坚 闵春艳 吴银生 金俊杰 秦昆明[2,3,4] 

机构地区：[1]苏州市食品药品检验所,215104 [2]南京海昌中药集团有限公司 [3]江苏海昇药业有限公司 [4]南京中医药大学国家教育部中药炮制规范化及标准化工程研究中心

出　　处：《环球中医药》2015年第5期550-553,共4页Global Traditional Chinese Medicine

基　　金：南京市科技发展计划(201007005);江苏省科技支撑计划工业项目(BE2012011);南京市科技公共服务平台建设项目(201105007);江苏省企业研究生工作站建设项目

摘　　要：目的研究甘松的挥发性成分。方法采用水蒸汽蒸馏法提取甘松中的挥发性成分,用气相色谱—质谱(GC-MS)联用仪进行分析鉴定,并采用峰面积归一化法测定了各成分的相对含量。结果共分离出135个化学成分,其中29个化学成分匹配度都在85%以上,占挥发油总量的20.51%。其中含量高于1%成分的有4个,以白菖烯含量最高(7.46%),其次是β-紫罗兰酮(3.44%)、异戊酸(2.19%)和β-橄榄烯(1.30%)。结论甘松挥发油中主要化学成分以萜类化合物为主,以倍半萜种数最多,且多是15个碳以下的小分子化合物。Objective To study the volatile component of nardostachys root. Methods The vola-tile components in nardostachys root were extracted by using steam distillation method, and analyzed by u-sing gas chromatography-mass spectroscopy （ GS-MS） . The relative content of each component was deter-mined by peak area normalization method. Results A total of 135 chemical compositions were isolated from nardostachys root, and the matching-degree of 29 chemical components among the 135 chemical was more than 85%, which accounted for 20. 51% of the total volatile oil. There were 4 components with con-tents above 1%. The highest component was calarene （7. 46%）, followed byβ-ionone （3. 44%）, isova-leric acid （2. 19%） andβ-Maaliene （1. 30%）. Conclusion The major components in nardostachys root were terpenes, which tend to be small molecule compounds with less than 15 carbon.

关 键 词：甘松 挥发油 气相色谱-质谱 

分 类 号：R284.1[医药卫生—中药学]