HPV检测与宫颈液基细胞学检查在宫颈癌筛查诊断价值对比研究  

Comparative analysis of HPV testing and TCT in screening of cervical cancer

作　　者：孔庆东[1] 

机构地区：[1]沈阳市苏家屯区妇婴医院PCR实验室,辽宁沈阳110101

出　　处：《中外医疗》2015年第3期18-19,共2页China & Foreign Medical Treatment

摘　　要：目的对比基于PCR的HPV检测与液基细胞学检查(TCT)在宫颈癌筛查中临床价值。方法选取该院2012年3月—2013年3月进行宫颈癌筛查的1209例女性为研究对象,其中932例患者采用HPV检测,277例患者采用TCT检测,对比两种检测方法灵敏度及特异度。结果 HPV检测法HPV阳性率为56.0%,TCT检测法HPV阳性率为50.5%,两种检测方法阳性率差异无统计学意义(P=0.28)。但HPV检测法在敏感度为和准确度上均显著高于TCT检测法。结论 HPV检测具有快速、灵敏的检测优势,并可以对患者感染的HPV进行分型鉴定,有利于临床上及早诊断高危型HPV,从而准确确定检查对象宫颈癌发病风险。Objective To compare and analysis HPV testing and TCT in screening of cervical cancer and diagnostic value. Meth-ods 1209 of women were detected by HPV testing or TCT for screening of cervical cancer in March 2012~March 2013. 932 cases were detected by HPV testing and 277 cases were detected by TCT. Sensitivity and specificity of two methods were compared. Results There were no significant difference in positive rate in HPV testing and TCT （56.0%and 50.5%respectively, P=0.28）. But HPV testing displayed higher sensitivity and accuracy rate than TCT. Conclusions HPV testing was a fast and sensitive method in screening of cervical cancer. HPV testing could distinguish high risk and exactly evaluate the risk of cervical cancer.

关 键 词：HPV检测 PCR TCT 宫颈癌筛查 

分 类 号：R737.33[医药卫生—肿瘤]